Fasudil
An isoquinoline substituted by a (1,4-diazepan-1-yl)sulfonyl group at position 5. It is a Rho-kinase inhibitor and its hydrochloride hydrate form is approved for the treatment of cerebral vasospasm and cerebral ischemia. — ChEBI
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Identity & molecular properties
Source-linked values| CAS number | 103745-39-7 | ChEBI ↗ |
| Molecular formula | C14H17N3O2S | ChEBI ↗ |
| Molar mass | 291.376 g/mol | ChEBI ↗ |
| Monoisotopic mass | 291.10415 Da | ChEBI ↗ |
| Formal charge | 0 | ChEBI ↗ |
| ChEBI identifier | CHEBI:43871 | ChEBI ↗ |
Cross-source molecular data
PubChem| Molar mass | 291.37 g/mol | PubChem ↗ |
| Exact mass | 291.10414797 Da | PubChem ↗ |
| Computed XLogP | 1 | PubChem ↗ |
| Topological polar surface area (Ų) | 70.7 | PubChem ↗ |
| H-bond donors | 1 | PubChem ↗ |
| H-bond acceptors | 5 | PubChem ↗ |
| Rotatable bonds | 2 | PubChem ↗ |
PubChem computed values are shown separately from the ChEBI record. An exact InChIKey match was used to connect the records. Molecular descriptors do not describe a supplied product’s purity, particle size or performance.
Names & structural identifiers
Copy any identifierfasudil5-(1,4-diazepan-1-ylsulfonyl)isoquinolineNGOGFTYYXHNFQH-UHFFFAOYSA-NO=S(=O)(c1cccc2cnccc12)N1CCCNCC1InChI=1S/C14H17N3O2S/c18-20(19,17-9-2-6-15-8-10-17)14-4-1-3-12-11-16-7-5-13(12)14/h1,3-5,7,11,15H,2,6,8-10H2Names & synonyms
Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.
Classification & relationships
ChEBI ontologyRoles recorded in ChEBI
Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.
Mass ↔ amount of substance
Calculated from sourced massUses 291.376 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.
Elemental composition
Theoretical mass fractionsCNSOHCalculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.
Research & patent references
Selected source associationsSources & record history
Checked 27 Sep 2026Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0
PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.