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Chemical substance record

Oxolane

109-99-9C4H8O72.107 g/mol

A cyclic ether that is butane in which one hydrogen from each methyl group is substituted by an oxygen. — ChEBI

Safety references

Safety documents & references

2 indexed references
US · NIOSH

Occupational chemical safety guide

Tetrahydrofuran

Read official guide
JP · NITE

Government GHS classification

H30-C-049-MHLW · FY2018

View classification

Find a product-specific SDS

Safety guides and government classification records are not a manufacturer’s SDS. Match supplier, product number, concentration, physical form, region and revision before using a document.

Identity & molecular properties

Source-linked values
CAS number109-99-9ChEBI ↗
Molecular formulaC4H8OChEBI ↗
Molar mass72.107 g/molChEBI ↗
Monoisotopic mass72.05751 DaChEBI ↗
Formal charge0ChEBI ↗
ChEBI identifierCHEBI:26911ChEBI ↗

Cross-source molecular data

PubChem
Molar mass72.11 g/molPubChem ↗
Exact mass72.057514874 DaPubChem ↗
Computed XLogP0.5PubChem ↗
Topological polar surface area (Ų)9.2PubChem ↗
H-bond donors0PubChem ↗
H-bond acceptors1PubChem ↗
Rotatable bonds0PubChem ↗

PubChem computed values are shown separately from the ChEBI record. An exact InChIKey match was used to connect the records. Molecular descriptors do not describe a supplied product’s purity, particle size or performance.

Names & structural identifiers

Copy any identifier
oxolane
oxolane
WYURNTSHIVDZCO-UHFFFAOYSA-N
C1CCOC1
InChI=1S/C4H8O/c1-2-4-5-3-1/h1-4H2

Classification & relationships

ChEBI ontology

Safety classification · Japan

NITE / Japanese government
Japan · FY2018 source classification
Tetrahydrofuran · H30-C-049-MHLW
EndpointReported classification
Skin corrosion/irritationCategory 2

Selected source-reported endpoints. Other endpoints, rationales and conditions remain in the original classification. Missing or unlisted information does not mean non-hazardous. This is not a global classification or transport decision.

Read the original NITE classification

Mass ↔ amount of substance

Calculated from sourced mass
Equivalent amount
0.0138683 mol

Uses 72.107 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions
C
Carbon · 4 atoms
66.63%
O
Oxygen · 1 atom
22.19%
H
Hydrogen · 8 atoms
11.18%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations

Sources & record history

Checked 27 Sep 2026
EMBL-EBI ChEBI · CHEBI:26911

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

NCBI PubChem · CID 8028 · retrieved 2026-09-27

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.