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Chemical substance record

Hydrocodone

125-29-1C18H21NO3299.37 g/mol
Organic/Inorganic Small MoleculeChEBI source record

A morphinane-like compound that is a semi-synthetic opioid synthesized from codeine. — ChEBI

Safety references

Safety documents & references

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Identity & molecular properties

Source-linked values
CAS number125-29-1ChEBI ↗
Molecular formulaC18H21NO3ChEBI ↗
Molar mass299.37 g/molChEBI ↗
Monoisotopic mass299.15214 DaChEBI ↗
Formal charge0ChEBI ↗
ChEBI identifierCHEBI:5779ChEBI ↗

Cross-source molecular data

PubChem
Molar mass299.4 g/molPubChem ↗
Exact mass299.15214353 DaPubChem ↗
Computed XLogP2.2PubChem ↗
Topological polar surface area (Ų)38.8PubChem ↗
H-bond donors0PubChem ↗
H-bond acceptors4PubChem ↗
Rotatable bonds1PubChem ↗

PubChem computed values are shown separately from the ChEBI record. An exact InChIKey match was used to connect the records. Molecular descriptors do not describe a supplied product’s purity, particle size or performance.

Names & structural identifiers

Copy any identifier
hydrocodone
3-methoxy-17-methyl-4,5alpha-epoxymorphinan-6-one
LLPOLZWFYMWNKH-CMKMFDCUSA-N
[H][C@@]12CCC(=O)[C@@H]3Oc4c(OC)ccc5c4[C@@]31CCN(C)[C@@H]2C5
InChI=1S/C18H21NO3/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19/h3,6,11-12,17H,4-5,7-9H2,1-2H3/t11-,12+,17-,18-/m0/s1

Names & synonyms

3-methoxy-17-methyl-4,5alpha-epoxymorphinan-6-onehidrocodonahydrocodonum

Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.

Classification & relationships

ChEBI ontology
organic heteropentacyclic compoundChEBI parent class · 38164 ↗morphinane-like compoundChEBI parent class · 83818 ↗
organic heterocyclic compoundorganic molecular entity

Roles recorded in ChEBI

opioid analgesicantitussivemu-opioid receptor agonist

Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.

Mass ↔ amount of substance

Calculated from sourced mass
Equivalent amount
0.00334035 mol

Uses 299.37 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions
C
Carbon · 18 atoms
72.22%
O
Oxygen · 3 atoms
16.03%
H
Hydrogen · 21 atoms
7.07%
N
Nitrogen · 1 atom
4.68%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations
Production and characterization of high-affinity monoclonal antibodies against morphine. ↗Molecular immunology · 1988 Sep · PMID 3211162
DE415097 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.
DE623821 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.
US2715626 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.
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Sources & record history

Checked 27 Sep 2026
EMBL-EBI ChEBI · CHEBI:5779

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

NCBI PubChem · CID 5284569 · retrieved 2026-09-27

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.

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