Chemical substance record

Suramin sodium

129-46-4C₅₁H₃₄N₆O₂₃S₆.₆Na1429.194 g/mol

Salt and Compound WithChEBI source record

An organic sodium salt that is the hexasodium salt of suramin. It is an FDA approved drug for African sleeping sickness and river blindness. — ChEBI

Safety references

Safety documents & references

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Identity & molecular properties

Source-linked values

CAS number	129-46-4	ChEBI ↗
Molecular formula	C₅₁H₃₄N₆O₂₃S₆.₆Na	ChEBI ↗
Molar mass	1429.194 g/mol	ChEBI ↗
Monoisotopic mass	1427.93857 Da	ChEBI ↗
Formal charge	0	ChEBI ↗
ChEBI identifier	CHEBI:9364	ChEBI ↗

Cross-source molecular data

PubChem

Molar mass	1429.2 g/mol	PubChem ↗
Exact mass	1427.9385741 Da	PubChem ↗

PubChem computed values are shown separately from the ChEBI record. An exact InChIKey match was used to connect the records. Molecular descriptors do not describe a supplied product’s purity, particle size or performance.

Names & structural identifiers

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Source preferred name

suramin sodium

IUPAC name

hexasodium 8,8'-{carbonylbis[iminobenzene-3,1-diylcarbonylimino(4-methylbenzene-3,1-diyl)carbonylimino]}dinaphthalene-1,3,5-trisulfonate

InChIKey

VAPNKLKDKUDFHK-UHFFFAOYSA-H

SMILES

Cc1ccc(C(=O)Nc2ccc(S(=O)(=O)[O-])c3cc(S(=O)(=O)[O-])cc(S(=O)(=O)[O-])c23)cc1NC(=O)c1cccc(NC(=O)Nc2cccc(C(=O)Nc3cc(C(=O)Nc4ccc(S(=O)(=O)[O-])c5cc(S(=O)(=O)[O-])cc(S(=O)(=O)[O-])c45)ccc3C)c2)c1.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]

InChI

InChI=1S/C51H40N6O23S6.6Na/c1-25-9-11-29(49(60)54-37-13-15-41(83(69,70)71)35-21-33(81(63,64)65)23-43(45(35)37)85(75,76)77)19-39(25)56-47(58)27-5-3-7-31(17-27)52-51(62)53-32-8-4-6-28(18-32)48(59)57-40-20-30(12-10-26(40)2)50(61)55-38-14-16-42(84(72,73)74)36-22-34(82(66,67)68)24-44(46(36)38)86(78,79)80;;;;;;/h3-24H,1-2H3,(H,54,60)(H,55,61)(H,56,58)(H,57,59)(H2,52,53,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80);;;;;;/q;6*+1/p-6

Names & synonyms

AntrypolBayer 205Fourneau 309Germaninhexasodium 8,8'-{carbonylbis[iminobenzene-3,1-diylcarbonylimino(4-methylbenzene-3,1-diyl)carbonylimino]}dinaphthalene-1,3,5-trisulfonateMoranylNaganinNaganineNaganinumNaganolNaphuride sodiumsuramina de sodio

Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.

Classification & relationships

ChEBI ontology

organic sodium saltChEBI parent class · 38700 ↗

organic salt

Roles recorded in ChEBI

renoprotective agentantinematodal drugantineoplastic agenttrypanocidal drugEC 2.7.11.13 (protein kinase C) inhibitorGABA-gated chloride channel antagonistangiogenesis inhibitorGABA antagonistryanodine receptor agonistapoptosis inhibitor

Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.

Mass ↔ amount of substance

Calculated from sourced mass

Amount

Input unit

Equivalent amount

0.000699695 mol

Uses 1429.194 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions

S

Sulfur · 66 atoms

65.36%

C

Carbon · 51 atoms

18.92%

O

Oxygen · 23 atoms

11.36%

N

Nitrogen · 6 atoms

2.60%

H

Hydrogen · 34 atoms

1.06%

Na

Sodium · 1 atom

0.71%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations

Suramin sodium. CI 1003, Metaret, suramin, suramin hexasodium. ↗Drugs in R&D · 1999 Dec · PMID 10763460

[Cellular partition and storage mechanism of Bayer 205 (Germanin) in the tissues]. ↗Acta physiologica Academiae Scientiarum Hungaricae · 1952 · PMID 13065125

US4737521 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.

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Sources & record history

Checked 27 Sep 2026

Identity, formula, mass, synonyms & ontologyEMBL-EBI ChEBI · CHEBI:9364

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

Additional molecular descriptorsNCBI PubChem · CID 5360 · retrieved 2026-09-27

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.

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