Streptozocin
An N-nitrosourea that is an antibiotic produced by Streptomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals. — ChEBI
Safety documents & references
1 indexed referencesFind a product-specific SDS
Safety guides and government classification records are not a manufacturer’s SDS. Match supplier, product number, concentration, physical form, region and revision before using a document.
Identity & molecular properties
Source-linked values| CAS number | 18883-66-4 | ChEBI ↗ |
| Molecular formula | C8H15N3O7 | ChEBI ↗ |
| Molar mass | 265.222 g/mol | ChEBI ↗ |
| Monoisotopic mass | 265.091 Da | ChEBI ↗ |
| Formal charge | 0 | ChEBI ↗ |
| ChEBI identifier | CHEBI:9288 | ChEBI ↗ |
Cross-source molecular data
PubChem| Molar mass | 265.22 g/mol | PubChem ↗ |
| Exact mass | 265.09099983 Da | PubChem ↗ |
| Computed XLogP | -1.4 | PubChem ↗ |
| Topological polar surface area (Ų) | 152 | PubChem ↗ |
| H-bond donors | 5 | PubChem ↗ |
| H-bond acceptors | 8 | PubChem ↗ |
| Rotatable bonds | 2 | PubChem ↗ |
PubChem computed values are shown separately from the ChEBI record. An exact InChIKey match was used to connect the records. Molecular descriptors do not describe a supplied product’s purity, particle size or performance.
Names & structural identifiers
Copy any identifierstreptozocin2-deoxy-2-{[methyl(nitroso)carbamoyl]amino}-alpha-D-glucopyranoseZSJLQEPLLKMAKR-GKHCUFPYSA-NCN(N=O)C(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OInChI=1S/C8H15N3O7/c1-11(10-17)8(16)9-4-6(14)5(13)3(2-12)18-7(4)15/h3-7,12-15H,2H2,1H3,(H,9,16)/t3-,4-,5-,6-,7+/m1/s1Names & synonyms
Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.
Classification & relationships
ChEBI ontologyRoles recorded in ChEBI
Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.
Safety classification · Japan
NITE / Japanese government1-Methyl-1-nitroso-3-［(2S,3R,4R,5S,6R)‐2,4,5‐trihydroxy‐6‐(hydroxymethyl)oxsan-3-yl］urea, (alias Streptozocin) · 21A3750
| Endpoint | Reported classification |
|---|---|
| Acute toxicity （Oral） | Category 3 |
| Germ cell mutagenicity | Category 2 |
| Carcinogenicity | Category 2 |
| Reproductive toxicity | Category 2 |
| Specific target organ toxicity - Single exposure | Category 1 (pancreas) |
| Specific target organ toxicity - Repeated exposure | Category 1 (pancreas, kidney, liver) |
Selected source-reported endpoints. Other endpoints, rationales and conditions remain in the original classification. Missing or unlisted information does not mean non-hazardous. This is not a global classification or transport decision.
Read the original NITE classificationMass ↔ amount of substance
Calculated from sourced massUses 265.222 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.
Elemental composition
Theoretical mass fractionsOCNHCalculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.
Research & patent references
Selected source associationsSources & record history
Checked 27 Sep 2026Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0
PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.