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Chemical substance record

Nimetazepam

2011-67-8C16H13N3O3295.298 g/mol
Organic/Inorganic Small MoleculeChEBI source record

A nitrazepam which is substituted at positions 1 by a methyl group. It is used as an anticonvulsant and as a hypnotic for the short-term management of insomnia. — ChEBI

Safety references

Safety documents & references

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Identity & molecular properties

Source-linked values
CAS number2011-67-8ChEBI ↗
Molecular formulaC16H13N3O3ChEBI ↗
Molar mass295.298 g/molChEBI ↗
Monoisotopic mass295.09569 DaChEBI ↗
Formal charge0ChEBI ↗
ChEBI identifierCHEBI:31912ChEBI ↗

Cross-source molecular data

PubChem
Molar mass295.29 g/molPubChem ↗
Exact mass295.09569129 DaPubChem ↗
Computed XLogP2.2PubChem ↗
Topological polar surface area (Ų)78.5PubChem ↗
H-bond donors0PubChem ↗
H-bond acceptors4PubChem ↗
Rotatable bonds1PubChem ↗

PubChem computed values are shown separately from the ChEBI record. An exact InChIKey match was used to connect the records. Molecular descriptors do not describe a supplied product’s purity, particle size or performance.

Names & structural identifiers

Copy any identifier
nimetazepam
1-methyl-7-nitro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
GWUSZQUVEVMBPI-UHFFFAOYSA-N
CN1C(=O)CN=C(c2ccccc2)c2cc([N+](=O)[O-])ccc21
InChI=1S/C16H13N3O3/c1-18-14-8-7-12(19(21)22)9-13(14)16(17-10-15(18)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3

Names & synonyms

1-methyl-7-nitro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-oneDormalonEriminnimetazepamum

Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.

Classification & relationships

ChEBI ontology
1,4-benzodiazepinoneChEBI parent class · 35500 ↗C-nitro compoundChEBI parent class · 35716 ↗
organic heterocyclic compoundorganic molecular entity

Roles recorded in ChEBI

anticonvulsantsedativeGABA modulatorantispasmodic drug

Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.

Mass ↔ amount of substance

Calculated from sourced mass
Equivalent amount
0.00338641 mol

Uses 295.298 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions
C
Carbon · 16 atoms
65.08%
O
Oxygen · 3 atoms
16.25%
N
Nitrogen · 3 atoms
14.23%
H
Hydrogen · 13 atoms
4.44%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations
Comparative metabolic study of nimetazepam and its desmethyl derivative (nitrazepam) in rats. ↗Xenobiotica; the fate of foreign compounds in biological systems · 1975 Apr · PMID 1154804
Comparative metabolic study of nimetazepam and its desmethyl derivative (nitrazepam) in dogs. ↗Xenobiotica; the fate of foreign compounds in biological systems · 1976 Feb · PMID 1274372
DE1816046 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.
US3109843 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.
US3121114 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.
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Sources & record history

Checked 27 Sep 2026
EMBL-EBI ChEBI · CHEBI:31912

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

NCBI PubChem · CID 4496 · retrieved 2026-09-27

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.

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