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Chemical substance record

Suprofen

40828-46-4C14H12O3S260.314 g/mol
Organic/Inorganic Small MoleculeChEBI source record

An aromatic ketone that is thiophene substituted at C-2 by a 4-(1-carboxyethyl)benzoyl group. — ChEBI

Safety references

Safety documents & references

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Identity & molecular properties

Source-linked values
CAS number40828-46-4ChEBI ↗
Molecular formulaC14H12O3SChEBI ↗
Molar mass260.314 g/molChEBI ↗
Monoisotopic mass260.05072 DaChEBI ↗
Formal charge0ChEBI ↗
ChEBI identifierCHEBI:9362ChEBI ↗

Cross-source molecular data

PubChem
Molar mass260.31 g/molPubChem ↗
Exact mass260.05071541 DaPubChem ↗
Computed XLogP3.3PubChem ↗
Topological polar surface area (Ų)82.6PubChem ↗
H-bond donors1PubChem ↗
H-bond acceptors4PubChem ↗
Rotatable bonds4PubChem ↗

PubChem computed values are shown separately from the ChEBI record. An exact InChIKey match was used to connect the records. Molecular descriptors do not describe a supplied product’s purity, particle size or performance.

Names & structural identifiers

Copy any identifier
suprofen
2-[4-(thiophen-2-ylcarbonyl)phenyl]propanoic acid
MDKGKXOCJGEUJW-UHFFFAOYSA-N
CC(C(=O)O)c1ccc(C(=O)c2cccs2)cc1
InChI=1S/C14H12O3S/c1-9(14(16)17)10-4-6-11(7-5-10)13(15)12-3-2-8-18-12/h2-9H,1H3,(H,16,17)

Names & synonyms

2-[4-(thiophen-2-ylcarbonyl)phenyl]propanoic acidsuprofenesuprofenum

Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.

Classification & relationships

ChEBI ontology
monocarboxylic acidChEBI parent class · 25384 ↗thiophenesChEBI parent class · 26961 ↗aromatic ketoneChEBI parent class · 76224 ↗
carboxylic acidketoneorganosulfur compoundorganic heterocyclic compoundorganic molecular entity

Roles recorded in ChEBI

non-steroidal anti-inflammatory drugnon-narcotic analgesicEC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitorantirheumatic drugperipheral nervous system drugdrug allergen

Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.

Mass ↔ amount of substance

Calculated from sourced mass
Equivalent amount
0.00384151 mol

Uses 260.314 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions
C
Carbon · 14 atoms
64.60%
O
Oxygen · 3 atoms
18.44%
S
Sulfur · 1 atom
12.32%
H
Hydrogen · 12 atoms
4.65%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations
Photoreactivity of tiaprofenic acid and suprofen using pig skin as an ex vivo model. ↗Journal of photochemistry and photobiology. B, Biology · 2000 Oct · PMID 11195850
Disposition of suprofen enantiomers in the cat. ↗Veterinary journal (London, England : 1997) · 2001 Jul · PMID 11409928
DE2353357 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.
US4035376 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.
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Sources & record history

Checked 27 Sep 2026
EMBL-EBI ChEBI · CHEBI:9362

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

NCBI PubChem · CID 5359 · retrieved 2026-09-27

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.

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