Chemical substance record

Cryptolepine

480-26-2C₁₆H₁₂N₂232.286 g/mol

Organic/Inorganic Small MoleculeChEBI source record

An organic heterotetracyclic compound that is 5H-indolo[3,2-b]quinoline in which the hydrogen at position N-5 is replaced by a methyl group. — ChEBI

Safety references

Safety documents & references

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Identity & molecular properties

Source-linked values

CAS number	480-26-2	ChEBI ↗
Molecular formula	C₁₆H₁₂N₂	ChEBI ↗
Molar mass	232.286 g/mol	ChEBI ↗
Monoisotopic mass	232.10005 Da	ChEBI ↗
Formal charge	0	ChEBI ↗
ChEBI identifier	CHEBI:3930	ChEBI ↗

Cross-source molecular data

PubChem

Molar mass	232.28 g/mol	PubChem ↗
Exact mass	232.100048391 Da	PubChem ↗
Computed XLogP	3.3	PubChem ↗
Topological polar surface area (Å²)	17.8	PubChem ↗
H-bond donors	0	PubChem ↗
H-bond acceptors	1	PubChem ↗
Rotatable bonds	0	PubChem ↗

PubChem computed values are shown separately from the ChEBI record. An exact InChIKey match was used to connect the records. Molecular descriptors do not describe a supplied product’s purity, particle size or performance.

Names & structural identifiers

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Source preferred name

cryptolepine

IUPAC name

5-methyl-5H-indolo[3,2-b]quinoline

InChIKey

KURWKDDWCJELSV-UHFFFAOYSA-N

SMILES

Cn1c2c3ccccc3nc-2cc2ccccc21

InChI

InChI=1S/C16H12N2/c1-18-15-9-5-2-6-11(15)10-14-16(18)12-7-3-4-8-13(12)17-14/h2-10H,1H3

Names & synonyms

5-methyl-5H-indolo[3,2-b]quinoline

Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.

Classification & relationships

ChEBI ontology

organonitrogen heterocyclic compoundChEBI parent class · 38101 ↗organic heterotetracyclic compoundChEBI parent class · 38163 ↗indole alkaloidChEBI parent class · 38958 ↗

organic heterocyclic compound organic molecular entity

Roles recorded in ChEBI

antineoplastic agentantimalarialcysteine protease inhibitoranti-inflammatory agentplant metabolite

Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.

Mass ↔ amount of substance

Calculated from sourced mass

Amount

Input unit

Equivalent amount

0.00430504 mol

Uses 232.286 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions

C

Carbon · 16 atoms

82.73%

N

Nitrogen · 2 atoms

12.06%

H

Hydrogen · 12 atoms

5.21%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations

Cryptolepine, isolated from Sida acuta, sensitizes human gastric adenocarcinoma cells to TRAIL-induced apoptosis. ↗Phytotherapy research : PTR · 2011 Jan · PMID 20623717

Probing ¹³C chemical shielding tensors in cryptolepine and two bromo-substituted analogs for antiplasmodial activity. ↗Journal of molecular modeling · 2011 Dec · PMID 21369934

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Sources & record history

Checked 27 Sep 2026

Identity, formula, mass, synonyms & ontologyEMBL-EBI ChEBI · CHEBI:3930

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

Additional molecular descriptorsNCBI PubChem · CID 82143 · retrieved 2026-09-27

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.

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