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Chemical substance record

Kojic acid

501-30-4C6H6O4142.11 g/mol

A pyranone that is 4H-pyran substituted by a hydroxy group at position 5, a hydroxymethyl group at position 2 and an oxo group at position 4. It has been isolated from the fungus Aspergillus oryzae. — ChEBI

Safety references

Safety documents & references

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Identity & molecular properties

Source-linked values
CAS number501-30-4ChEBI ↗
Molecular formulaC6H6O4ChEBI ↗
Molar mass142.11 g/molChEBI ↗
Monoisotopic mass142.02661 DaChEBI ↗
Formal charge0ChEBI ↗
ChEBI identifierCHEBI:43572ChEBI ↗

Cross-source molecular data

PubChem
Molar mass142.11 g/molPubChem ↗
Exact mass142.02660867 DaPubChem ↗
Computed XLogP-0.9PubChem ↗
Topological polar surface area (Ų)66.8PubChem ↗
H-bond donors2PubChem ↗
H-bond acceptors4PubChem ↗
Rotatable bonds1PubChem ↗

PubChem computed values are shown separately from the ChEBI record. An exact InChIKey match was used to connect the records. Molecular descriptors do not describe a supplied product’s purity, particle size or performance.

Names & structural identifiers

Copy any identifier
kojic acid
5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one
BEJNERDRQOWKJM-UHFFFAOYSA-N
O=c1cc(CO)occ1O
InChI=1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2

Names & synonyms

5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one

Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.

Classification & relationships

ChEBI ontology

Roles recorded in ChEBI

EC 1.14.18.1 (tyrosinase) inhibitorNF-kappaB inhibitorAspergillus metaboliteskin lightening agentEC 1.10.3.1 (catechol oxidase) inhibitorEC 1.10.3.2 (laccase) inhibitorEC 1.13.11.24 (quercetin 2,3-dioxygenase) inhibitorEC 1.4.3.3 (D-amino-acid oxidase) inhibitor

Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.

Mass ↔ amount of substance

Calculated from sourced mass
Equivalent amount
0.0070368 mol

Uses 142.11 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions
C
Carbon · 6 atoms
50.71%
O
Oxygen · 4 atoms
45.03%
H
Hydrogen · 6 atoms
4.26%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations
Specificity and kinetics of Rhodotorula gracilis D-amino acid oxidase. ↗Biochimica et biophysica acta · 1992 Mar 27 · PMID 1348188
AU2012268879 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.
JP2013017408 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.

Sources & record history

Checked 27 Sep 2026
EMBL-EBI ChEBI · CHEBI:43572

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

NCBI PubChem · CID 3840 · retrieved 2026-09-27

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.