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Chemical substance record

Erteberel

533884-09-2C18H18O3282.339 g/mol

An organic heterotricyclic compound that is 1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromene substituted by 4-hydroxyphenyl and hydroxy groups at positions 4 and 8, respectively (the 3aS,4R,9bR-stereoisomer). It is an estrogen receptor β agonist and exhibits antineoplastic activity. — ChEBI

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Identity & molecular properties

Source-linked values
CAS number533884-09-2ChEBI ↗
Molecular formulaC18H18O3ChEBI ↗
Molar mass282.339 g/molChEBI ↗
Monoisotopic mass282.12559 DaChEBI ↗
Formal charge0ChEBI ↗
ChEBI identifierCHEBI:231600ChEBI ↗

Cross-source molecular data

PubChem
Molar mass282.3 g/molPubChem ↗
Exact mass282.125594432 DaPubChem ↗
Computed XLogP4PubChem ↗
Topological polar surface area (Ų)49.7PubChem ↗
H-bond donors2PubChem ↗
H-bond acceptors3PubChem ↗
Rotatable bonds1PubChem ↗

PubChem computed values are shown separately from the ChEBI record. An exact InChIKey match was used to connect the records. Molecular descriptors do not describe a supplied product’s purity, particle size or performance.

Names & structural identifiers

Copy any identifier
erteberel
(3aS,4R,9bR)-4-(4-hydroxyphenyl)-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-ol
XIESSJVMWNJCGZ-VKJFTORMSA-N
[H][C@]12CCC[C@@]1([H])c1cc(O)ccc1O[C@@]2([H])c1ccc(O)cc1
InChI=1S/C18H18O3/c19-12-6-4-11(5-7-12)18-15-3-1-2-14(15)16-10-13(20)8-9-17(16)21-18/h4-10,14-15,18-20H,1-3H2/t14-,15+,18+/m1/s1

Names & synonyms

(3aS,4R,9bR)-4-(4-hydroxyphenyl)-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-olerteberelum

Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.

Classification & relationships

ChEBI ontology

Roles recorded in ChEBI

antineoplastic agentestrogen receptor agonistapoptosis inducer

Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.

Mass ↔ amount of substance

Calculated from sourced mass
Equivalent amount
0.00354184 mol

Uses 282.339 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions
C
Carbon · 18 atoms
76.57%
O
Oxygen · 3 atoms
17.00%
H
Hydrogen · 18 atoms
6.43%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations

Sources & record history

Checked 27 Sep 2026
EMBL-EBI ChEBI · CHEBI:231600

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

NCBI PubChem · CID 10286159 · retrieved 2026-09-27

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.