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Chemical substance record

Pentostatin

53910-25-1C11H16N4O4268.273 g/mol

A member of the class of coformycins that is coformycin in which the hydroxy group at position 2' is replaced with a hydrogen. It is a drug used for the treatment of hairy cell leukaemia. — ChEBI

Safety references

Safety documents & references

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Identity & molecular properties

Source-linked values
CAS number53910-25-1ChEBI ↗
Molecular formulaC11H16N4O4ChEBI ↗
Molar mass268.273 g/molChEBI ↗
Monoisotopic mass268.11716 DaChEBI ↗
Formal charge0ChEBI ↗
ChEBI identifierCHEBI:27834ChEBI ↗

Cross-source molecular data

PubChem
Molar mass268.27 g/molPubChem ↗
Exact mass268.11715500 DaPubChem ↗
Computed XLogP-2.1PubChem ↗
Topological polar surface area (Ų)112PubChem ↗
H-bond donors4PubChem ↗
H-bond acceptors6PubChem ↗
Rotatable bonds2PubChem ↗

PubChem computed values are shown separately from the ChEBI record. An exact InChIKey match was used to connect the records. Molecular descriptors do not describe a supplied product’s purity, particle size or performance.

Names & structural identifiers

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pentostatin
(8R)-3-(2-deoxy-beta-D-erythro-pentofuranosyl)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol
FPVKHBSQESCIEP-JQCXWYLXSA-N
OC[C@H]1O[C@@H](n2cnc3c2N=CNC[C@H]3O)C[C@@H]1O
InChI=1S/C11H16N4O4/c16-3-8-6(17)1-9(19-8)15-5-14-10-7(18)2-12-4-13-11(10)15/h4-9,16-18H,1-3H2,(H,12,13)/t6-,7+,8+,9+/m0/s1

Names & synonyms

(8R)-3-(2-deoxy-beta-D-erythro-pentofuranosyl)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-olNipentpentostatinapentostatinepentostatinum

Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.

Classification & relationships

ChEBI ontology

Roles recorded in ChEBI

antimetaboliteantineoplastic agentEC 3.5.4.4 (adenosine deaminase) inhibitoranti-anaemic agentAspergillus metabolitebacterial metabolite

Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.

Mass ↔ amount of substance

Calculated from sourced mass
Equivalent amount
0.00372755 mol

Uses 268.273 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions
C
Carbon · 11 atoms
49.25%
O
Oxygen · 4 atoms
23.85%
N
Nitrogen · 4 atoms
20.88%
H
Hydrogen · 16 atoms
6.01%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations
Pentostatin (Nipent) in T-cell lymphomas. ↗Seminars in oncology · 2000 Apr · PMID 10877055
US20040181052 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.

Sources & record history

Checked 27 Sep 2026
EMBL-EBI ChEBI · CHEBI:27834

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

NCBI PubChem · CID 439693 · retrieved 2026-09-27

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.