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Chemical substance record

Biotin

58-85-5C10H16N2O3S244.316 g/mol

An organic heterobicyclic compound that consists of 2-oxohexahydro-1H-thieno[3,4-d]imidazole having a valeric acid substituent attached to the tetrahydrothiophene ring. The parent of the class of biotins. — ChEBI

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Identity & molecular properties

Source-linked values
CAS number58-85-5ChEBI ↗
Molecular formulaC10H16N2O3SChEBI ↗
Molar mass244.316 g/molChEBI ↗
Monoisotopic mass244.08816 DaChEBI ↗
Formal charge0ChEBI ↗
ChEBI identifierCHEBI:15956ChEBI ↗

Cross-source molecular data

PubChem
Molar mass244.31 g/molPubChem ↗
Exact mass244.08816355 DaPubChem ↗
Computed XLogP0.3PubChem ↗
Topological polar surface area (Ų)104PubChem ↗
H-bond donors3PubChem ↗
H-bond acceptors4PubChem ↗
Rotatable bonds5PubChem ↗

PubChem computed values are shown separately from the ChEBI record. An exact InChIKey match was used to connect the records. Molecular descriptors do not describe a supplied product’s purity, particle size or performance.

Names & structural identifiers

Copy any identifier
biotin
5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid
YBJHBAHKTGYVGT-ZKWXMUAHSA-N
[H][C@]12CS[C@@H](CCCCC(=O)O)[C@@]1([H])NC(=O)N2
InChI=1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1

Names & synonyms

5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acidbiotinabiotinebiotinum

Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.

Classification & relationships

ChEBI ontology

Roles recorded in ChEBI

renoprotective agentcoenzymecofactorprosthetic grouphypoglycemic agentcardiovascular drugimmunosuppressive agentnutraceuticalanti-asthmatic agentmouse metabolite

Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.

Mass ↔ amount of substance

Calculated from sourced mass
Equivalent amount
0.00409306 mol

Uses 244.316 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions
C
Carbon · 10 atoms
49.16%
O
Oxygen · 3 atoms
19.65%
S
Sulfur · 1 atom
13.13%
N
Nitrogen · 2 atoms
11.47%
H
Hydrogen · 16 atoms
6.60%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations

Sources & record history

Checked 27 Sep 2026
EMBL-EBI ChEBI · CHEBI:15956

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

NCBI PubChem · CID 171548 · retrieved 2026-09-27

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.