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Chemical substance record

Furazolidone

67-45-8C8H7N3O5225.16 g/mol
Organic/Inorganic Small MoleculeChEBI source record

A member of the class of oxazolidines that is 1,3-oxazolidin-2-one in which the hydrogen attached to the nitrogen is replaced by an N-{[(5-nitro-2-furyl)methylene]amino} group. It has antibacterial and antiprotozoal properties, and is used in the treatment of giardiasis and cholera. — ChEBI

Safety references

Safety documents & references

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Identity & molecular properties

Source-linked values
CAS number67-45-8ChEBI ↗
Molecular formulaC8H7N3O5ChEBI ↗
Molar mass225.16 g/molChEBI ↗
Monoisotopic mass225.03857 DaChEBI ↗
Formal charge0ChEBI ↗
ChEBI identifierCHEBI:5195ChEBI ↗

Cross-source molecular data

PubChem
Molar mass225.16 g/molPubChem ↗
Exact mass225.03857033 DaPubChem ↗
Computed XLogP-0.1PubChem ↗
Topological polar surface area (Ų)101PubChem ↗
H-bond donors0PubChem ↗
H-bond acceptors6PubChem ↗
Rotatable bonds2PubChem ↗

PubChem computed values are shown separately from the ChEBI record. An exact InChIKey match was used to connect the records. Molecular descriptors do not describe a supplied product’s purity, particle size or performance.

Names & structural identifiers

Copy any identifier
furazolidone
3-{[(5-nitro-2-furyl)methylene]amino}-1,3-oxazolidin-2-one
PLHJDBGFXBMTGZ-UHFFFAOYSA-N
[H]C(=NN1CCOC1=O)c1ccc([N+](=O)[O-])o1
InChI=1S/C8H7N3O5/c12-8-10(3-4-15-8)9-5-6-1-2-7(16-6)11(13)14/h1-2,5H,3-4H2

Names & synonyms

3-{[(5-nitro-2-furyl)methylene]amino}-1,3-oxazolidin-2-oneFurazolidonaFurazolidonum

Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.

Classification & relationships

ChEBI ontology
oxazolidinesChEBI parent class · 38329 ↗nitrofuran antibioticChEBI parent class · 87230 ↗
organic heterocyclic compoundorganic molecular entity

Roles recorded in ChEBI

antiinfective agentantibacterial drugEC 1.4.3.4 (monoamine oxidase) inhibitorantitrichomonal drug

Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.

Mass ↔ amount of substance

Calculated from sourced mass
Equivalent amount
0.00444129 mol

Uses 225.16 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions
C
Carbon · 8 atoms
42.68%
O
Oxygen · 5 atoms
35.53%
N
Nitrogen · 3 atoms
18.66%
H
Hydrogen · 7 atoms
3.13%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations
Furazolidone versus metronidazole in quadruple therapy for eradication of Helicobacter pylori in duodenal ulcer disease. ↗Alimentary pharmacology & therapeutics · 2000 Mar · PMID 10735922
The specificity of cross-reactivity: promiscuous antibody binding involves specific hydrogen bonds rather than nonspecific hydrophobic stickiness. ↗Protein science : a publication of the Protein Society · 2003 Oct · PMID 14500876
GB735136 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.
US2742462 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.
US2759931 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.
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Sources & record history

Checked 27 Sep 2026
EMBL-EBI ChEBI · CHEBI:5195

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

NCBI PubChem · CID 3435 · retrieved 2026-09-27

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.

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