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Chemical substance record

Didanosine

69655-05-6C10H12N4O3236.231 g/mol

A purine 2',3'-dideoxyribonucleoside that is inosine in which the hydroxy groups at both the 2' and the 3' positions on the sugar moiety have been replaced by hydrogen. An antiviral drug, it is used as a medication to treat HIV/AIDS. — ChEBI

Safety references

Safety documents & references

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Identity & molecular properties

Source-linked values
CAS number69655-05-6ChEBI ↗
Molecular formulaC10H12N4O3ChEBI ↗
Molar mass236.231 g/molChEBI ↗
Monoisotopic mass236.09094 DaChEBI ↗
Formal charge0ChEBI ↗
ChEBI identifierCHEBI:490877ChEBI ↗

Cross-source molecular data

PubChem
Molar mass236.23 g/molPubChem ↗
Exact mass236.09094026 DaPubChem ↗
Computed XLogP-1.2PubChem ↗
Topological polar surface area (Ų)88.7PubChem ↗
H-bond donors2PubChem ↗
H-bond acceptors5PubChem ↗
Rotatable bonds2PubChem ↗

PubChem computed values are shown separately from the ChEBI record. An exact InChIKey match was used to connect the records. Molecular descriptors do not describe a supplied product’s purity, particle size or performance.

Names & structural identifiers

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didanosine
2',3'-dideoxyinosine
BXZVVICBKDXVGW-NKWVEPMBSA-N
O=c1ncnc2c1ncn2[C@H]1CC[C@@H](CO)O1
InChI=1S/C10H12N4O3/c15-3-6-1-2-7(17-6)14-5-13-8-9(14)11-4-12-10(8)16/h4-7,15H,1-3H2,(H,11,12,16)/t6-,7+/m0/s1

Names & synonyms

2',3'-dideoxyinosinedidanosinadidanosinum

Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.

Classification & relationships

ChEBI ontology

Roles recorded in ChEBI

geroprotectorantiviral agentantitubercular agentantimetaboliteantineoplastic agentantiviral drugHIV-1 reverse transcriptase inhibitorEC 2.4.2.1 (purine-nucleoside phosphorylase) inhibitoranti-HIV agent

Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.

Mass ↔ amount of substance

Calculated from sourced mass
Equivalent amount
0.00423314 mol

Uses 236.231 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions
C
Carbon · 10 atoms
50.84%
N
Nitrogen · 4 atoms
23.72%
O
Oxygen · 3 atoms
20.32%
H
Hydrogen · 12 atoms
5.12%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations
Synthesis and anti-HIV activity of isonucleosides. ↗Journal of medicinal chemistry · 1992 Jun 26 · PMID 1619614
EP206497 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.

Sources & record history

Checked 27 Sep 2026
EMBL-EBI ChEBI · CHEBI:490877

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

NCBI PubChem · CID 135398739 · retrieved 2026-09-27

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.