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Chemical substance record

Lidocaine

137-58-6C14H22N2O234.343 g/mol

The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline. — ChEBI

Safety references

Safety documents & references

1 indexed references
JP · NITE

Government GHS classification

23A5145 · FY2011

View classification

Find a product-specific SDS

Safety guides and government classification records are not a manufacturer’s SDS. Match supplier, product number, concentration, physical form, region and revision before using a document.

Identity & molecular properties

Source-linked values
CAS number137-58-6ChEBI ↗
Molecular formulaC14H22N2OChEBI ↗
Molar mass234.343 g/molChEBI ↗
Monoisotopic mass234.17321 DaChEBI ↗
Formal charge0ChEBI ↗
ChEBI identifierCHEBI:6456ChEBI ↗

Cross-source molecular data

PubChem
Molar mass234.34 g/molPubChem ↗
Exact mass234.173213330 DaPubChem ↗
Computed XLogP2.3PubChem ↗
Topological polar surface area (Ų)32.3PubChem ↗
H-bond donors1PubChem ↗
H-bond acceptors2PubChem ↗
Rotatable bonds5PubChem ↗

PubChem computed values are shown separately from the ChEBI record. An exact InChIKey match was used to connect the records. Molecular descriptors do not describe a supplied product’s purity, particle size or performance.

Names & structural identifiers

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lidocaine
N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide
NNJVILVZKWQKPM-UHFFFAOYSA-N
CCN(CC)CC(=O)Nc1c(C)cccc1C
InChI=1S/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17)

Names & synonyms

LidodermN-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide

Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.

Classification & relationships

ChEBI ontology

Roles recorded in ChEBI

antiviral agentantiinfective agentanxiolytic druganalgesiccardiovascular drugantineoplastic agentantihypertensive agentxenobioticlocal anaestheticanti-arrhythmia drug

Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.

Safety classification · Japan

NITE / Japanese government
Japan · FY2011 source classification
Lidocaine · 23A5145
EndpointReported classification
Acute toxicity (Oral)Category 4
Skin sensitizationCategory 1
Reproductive toxicityClassification not possible, Additional category: Effects on or via lactation
Specific target organ toxicity - Single exposureCategory 1 (blood, nervous system, cardiovascular system)
Specific target organ toxicity - Repeated exposureCategory 1 (nervous system, cardiovascular system, blood)

Selected source-reported endpoints. Other endpoints, rationales and conditions remain in the original classification. Missing or unlisted information does not mean non-hazardous. This is not a global classification or transport decision.

Read the original NITE classification

Mass ↔ amount of substance

Calculated from sourced mass
Equivalent amount
0.00426725 mol

Uses 234.343 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions
C
Carbon · 14 atoms
71.76%
N
Nitrogen · 2 atoms
11.95%
H
Hydrogen · 22 atoms
9.46%
O
Oxygen · 1 atom
6.83%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations
Identification of lidocaine and its metabolites in post-administration equine urine by ELISA and MS/MS. ↗Journal of veterinary pharmacology and therapeutics · 2000 Aug · PMID 11106996
GB706409 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.
GB758224 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.
US2441498 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.

Sources & record history

Checked 27 Sep 2026
EMBL-EBI ChEBI · CHEBI:6456

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

NCBI PubChem · CID 3676 · retrieved 2026-09-27

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.