Skip to content
[P]pubcas
Independent chemical reference Compare
Home/Chemicals/144-82-1
Chemical substance record

Sulfamethizole

144-82-1C9H10N4O2S2270.339 g/mol
Organic/Inorganic Small MoleculeChEBI source record

A sulfonamide consisting of a 1,3,4-thiadiazole nucleus with a methyl substituent at C-5 and a 4-aminobenzenesulfonamido group at C-2. — ChEBI

Safety references

Safety documents & references

Supplier matching matters

Find the safety document for your specific supplier, product number and grade.

Find a product-specific SDS

Search SDS PDFs Sigma-Aldrich Thermo Fisher

Safety guides and government classification records are not a manufacturer’s SDS. Match supplier, product number, concentration, physical form, region and revision before using a document.

Identity & molecular properties

Source-linked values
CAS number144-82-1ChEBI ↗
Molecular formulaC9H10N4O2S2ChEBI ↗
Molar mass270.339 g/molChEBI ↗
Monoisotopic mass270.02452 DaChEBI ↗
Formal charge0ChEBI ↗
ChEBI identifierCHEBI:9331ChEBI ↗

Cross-source molecular data

PubChem
Molar mass270.3 g/molPubChem ↗
Exact mass270.02451792 DaPubChem ↗
Computed XLogP0.5PubChem ↗
Topological polar surface area (Ų)135PubChem ↗
H-bond donors2PubChem ↗
H-bond acceptors7PubChem ↗
Rotatable bonds3PubChem ↗

PubChem computed values are shown separately from the ChEBI record. An exact InChIKey match was used to connect the records. Molecular descriptors do not describe a supplied product’s purity, particle size or performance.

Names & structural identifiers

Copy any identifier
sulfamethizole
4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide
VACCAVUAMIDAGB-UHFFFAOYSA-N
Cc1nnc(NS(=O)(=O)c2ccc(N)cc2)s1
InChI=1S/C9H10N4O2S2/c1-6-11-12-9(16-6)13-17(14,15)8-4-2-7(10)3-5-8/h2-5H,10H2,1H3,(H,12,13)

Names & synonyms

4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamideRufolsulfamethizolsulfamethizolumsulfametizol

Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.

Classification & relationships

ChEBI ontology
sulfonamideChEBI parent class · 35358 ↗thiadiazolesChEBI parent class · 38099 ↗sulfonamide antibioticChEBI parent class · 87228 ↗
organosulfur compoundorganic heterocyclic compoundorganic molecular entity

Roles recorded in ChEBI

antimicrobial agentantibacterial agentantiinfective agentEC 2.5.1.15 (dihydropteroate synthase) inhibitorophthalmology drugdrug allergen

Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.

Mass ↔ amount of substance

Calculated from sourced mass
Equivalent amount
0.00369906 mol

Uses 270.339 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions
C
Carbon · 9 atoms
39.99%
S
Sulfur · 2 atoms
23.73%
N
Nitrogen · 4 atoms
20.72%
O
Oxygen · 2 atoms
11.84%
H
Hydrogen · 10 atoms
3.73%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations
Degeneracy and additional alloreactivity of drug-specific human alpha beta(+) T cell clones. ↗International immunology · 2001 Jul · PMID 11431418
Oxidation of sulfonamide antimicrobials by ferrate(VI) [Fe(VI)O4(2-)]. ↗Environmental science & technology · 2006 Dec 1 · PMID 17180970
US2447702 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.
Search PubMed Google Scholar

Sources & record history

Checked 27 Sep 2026
EMBL-EBI ChEBI · CHEBI:9331

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

NCBI PubChem · CID 5328 · retrieved 2026-09-27

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.

How this record was assembledSuggest a correction