Home/Chemicals/68-35-9

Chemical substance record

Sulfadiazine

68-35-9C₁₀H₁₀N₄O₂S250.283 g/mol

Organic/Inorganic Small MoleculeChEBI source record

A sulfonamide consisting of pyrimidine with a 4-aminobenzenesulfonamido group at the 2-position. — ChEBI

Safety references

Safety documents & references

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Identity & molecular properties

Source-linked values

CAS number	68-35-9	ChEBI ↗
Molecular formula	C₁₀H₁₀N₄O₂S	ChEBI ↗
Molar mass	250.283 g/mol	ChEBI ↗
Monoisotopic mass	250.05245 Da	ChEBI ↗
Formal charge	0	ChEBI ↗
ChEBI identifier	CHEBI:9328	ChEBI ↗

Cross-source molecular data

PubChem

Molar mass	250.28 g/mol	PubChem ↗
Exact mass	250.05244675 Da	PubChem ↗
Computed XLogP	-0.1	PubChem ↗
Topological polar surface area (Å²)	106	PubChem ↗
H-bond donors	2	PubChem ↗
H-bond acceptors	6	PubChem ↗
Rotatable bonds	3	PubChem ↗

PubChem computed values are shown separately from the ChEBI record. An exact InChIKey match was used to connect the records. Molecular descriptors do not describe a supplied product’s purity, particle size or performance.

Names & structural identifiers

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Source preferred name

sulfadiazine

IUPAC name

4-amino-N-(pyrimidin-2-yl)benzenesulfonamide

InChIKey

SEEPANYCNGTZFQ-UHFFFAOYSA-N

SMILES

Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1

InChI

InChI=1S/C10H10N4O2S/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10/h1-7H,11H2,(H,12,13,14)

Names & synonyms

4-amino-N-(pyrimidin-2-yl)benzenesulfonamidesulfadiazinasulfadiazinum

Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.

Classification & relationships

ChEBI ontology

sulfonamideChEBI parent class · 35358 ↗pyrimidinesChEBI parent class · 39447 ↗substituted anilineChEBI parent class · 48975 ↗sulfonamide antibioticChEBI parent class · 87228 ↗

organosulfur compound organic heterocyclic compound organic molecular entity

Roles recorded in ChEBI

antimicrobial agentantibacterial agentantiinfective agentantiparasitic agentxenobioticcoccidiostatantiprotozoal drugantimalarialEC 2.5.1.15 (dihydropteroate synthase) inhibitorEC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitor

Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.

Mass ↔ amount of substance

Calculated from sourced mass

Amount

Input unit

Equivalent amount

0.00399548 mol

Uses 250.283 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions

C

Carbon · 10 atoms

47.99%

N

Nitrogen · 4 atoms

22.39%

S

Sulfur · 1 atom

12.81%

O

Oxygen · 2 atoms

12.78%

H

Hydrogen · 10 atoms

4.03%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations

Degeneracy and additional alloreactivity of drug-specific human alpha beta(+) T cell clones. ↗International immunology · 2001 Jul · PMID 11431418

Drug-induced renal failure: update on new medications and unique mechanisms of nephrotoxicity. ↗The American journal of the medical sciences · 2003 Jun · PMID 12811231

GB557055 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.

US2407966 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.

US2410793 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.

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Sources & record history

Checked 27 Sep 2026

Identity, formula, mass, synonyms & ontologyEMBL-EBI ChEBI · CHEBI:9328

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

Additional molecular descriptorsNCBI PubChem · CID 5215 · retrieved 2026-09-27

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.

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