Chemical substance record

Tranylcypromine

155-09-9C₉H₁₁N133.194 g/mol

Organic/Inorganic Small MoleculeChEBI source record

A racemate comprising equal amounts of (1R,2S)- and (1S,2R)-2-phenylcyclopropan-1-amine. An irreversible monoamine oxidase inhibitor that is used as an antidepressant (INN tranylcypromine). — ChEBI

Safety references

Safety documents & references

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Identity & molecular properties

Source-linked values

CAS number	155-09-9	ChEBI ↗
Molecular formula	C₉H₁₁N	ChEBI ↗
Molar mass	133.194 g/mol	ChEBI ↗
Monoisotopic mass	133.08915 Da	ChEBI ↗
Formal charge	0	ChEBI ↗
ChEBI identifier	CHEBI:9652	ChEBI ↗

Names & structural identifiers

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Source preferred name

tranylcypromine

IUPAC name

rac-(1R,2S)-2-phenylcyclopropan-1-amine

Names & synonyms

rac-(1R,2S)-2-phenylcyclopropan-1-aminetranilciprominatranylcyprominum

Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.

Classification & relationships

ChEBI ontology

racemateChEBI parent class · 60911 ↗

Roles recorded in ChEBI

EC 1.14.99.66 (lysine-specific histone demethylase 1A) inhibitorantidepressantanxiolytic drugantipsychotic agentantineoplastic agentEC 1.4.3.4 (monoamine oxidase) inhibitorP450 inhibitorvasoconstrictor agent

Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.

Mass ↔ amount of substance

Calculated from sourced mass

Amount

Input unit

Equivalent amount

0.00750785 mol

Uses 133.194 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions

C

Carbon · 9 atoms

81.16%

N

Nitrogen · 1 atom

10.52%

H

Hydrogen · 11 atoms

8.32%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations

In vitro inhibition of cytochrome P450 enzymes in human liver microsomes by a potent CYP2A6 inhibitor, trans-2-phenylcyclopropylamine (tranylcypromine), and its nonamine analog, cyclopropylbenzene. ↗Drug metabolism and disposition: the biological fate of chemicals · 2001 Mar · PMID 11181487

Effects of stress and tranylcypromine on amphetamine-induced locomotor activity and GABA(B) receptor function in rat brain. ↗Life sciences · 2003 Jan 17 · PMID 12495786

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Sources & record history

Checked 27 Sep 2026

Identity, formula, mass, synonyms & ontologyEMBL-EBI ChEBI · CHEBI:9652

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.

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