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Chemical substance record

Osmium tetroxide

20816-12-0O4Os254.226 g/mol
Coordination CompoundChEBI source record

An osmium coordination entity consisting of four oxygen atoms bound to a central osmium atom via covalent double bonds. — ChEBI

Safety references

Safety documents & references

2 indexed references
US · NIOSH

Occupational chemical safety guide

Osmium tetroxide

Read official guide
JP · NITE

Government GHS classification

780 · FY2006

View classification

Find a product-specific SDS

Safety guides and government classification records are not a manufacturer’s SDS. Match supplier, product number, concentration, physical form, region and revision before using a document.

Identity & molecular properties

Source-linked values
CAS number20816-12-0ChEBI ↗
Molecular formulaO4OsChEBI ↗
Molar mass254.226 g/molChEBI ↗
Monoisotopic mass255.94114 DaChEBI ↗
Formal charge0ChEBI ↗
ChEBI identifierCHEBI:88215ChEBI ↗

Cross-source molecular data

PubChem
Molar mass254.2 g/molPubChem ↗
Exact mass255.94114 DaPubChem ↗

PubChem computed values are shown separately from the ChEBI record. An exact InChIKey match was used to connect the records. Molecular descriptors do not describe a supplied product’s purity, particle size or performance.

Names & structural identifiers

Copy any identifier
osmium tetroxide
tetraoxoosmium
VUVGYHUDAICLFK-UHFFFAOYSA-N
[O]=[Os](=[O])(=[O])=[O]
InChI=1S/4O.Os

Names & synonyms

tetraoxoosmium

Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.

Classification & relationships

ChEBI ontology

Roles recorded in ChEBI

NMR chemical shift reference compoundfixativeoxidising agentpoisonhistological dye

Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.

Safety classification · Japan

NITE / Japanese government
Japan · FY2006 source classification
osmium tetraoxide · 780
EndpointReported classification
Acute toxicity (Oral)Category 3
Acute toxicity (Inhalation: Vapours)Category 1
Skin corrosion/irritationCategory 1A-1C
Serious eye damage/eye irritationCategory 1
Specific target organ toxicity - Single exposureCategory 1 (respiratory system, liver, kidney, adrenal gland, spleen)
Specific target organ toxicity - Repeated exposureCategory 1 (respiratory system), Category 2 (kidney, liver, adrenal gland, spleen, hematopoietic system)

Selected source-reported endpoints. Other endpoints, rationales and conditions remain in the original classification. Missing or unlisted information does not mean non-hazardous. This is not a global classification or transport decision.

Read the original NITE classification

Mass ↔ amount of substance

Calculated from sourced mass
Equivalent amount
0.00393351 mol

Uses 254.226 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions
Os
Osmium · 1 atom
74.82%
O
Oxygen · 4 atoms
25.18%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations

Sources & record history

Checked 27 Sep 2026
EMBL-EBI ChEBI · CHEBI:88215

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

NCBI PubChem · CID 30318 · retrieved 2026-09-27

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.