Chemical substance record

Oxaprozin

21256-18-8C₁₈H₁₅NO₃293.322 g/mol

Organic/Inorganic Small MoleculeChEBI source record

A monocarboxylic acid that is a propionic acid derivative having a 4,5-diphenyl-1,3-oxazol-2-yl substituent at position 3. It is non-steroidal anti-inflammatory drug commonly used to relieve the pain and inflammatory responses associated with osteoarthritis and rheumatoid arthritis. — ChEBI

Safety references

Safety documents & references

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Identity & molecular properties

Source-linked values

CAS number	21256-18-8	ChEBI ↗
Molecular formula	C₁₈H₁₅NO₃	ChEBI ↗
Molar mass	293.322 g/mol	ChEBI ↗
Monoisotopic mass	293.10519 Da	ChEBI ↗
Formal charge	0	ChEBI ↗
ChEBI identifier	CHEBI:7822	ChEBI ↗

Cross-source molecular data

PubChem

Molar mass	293.3 g/mol	PubChem ↗
Exact mass	293.10519334 Da	PubChem ↗
Computed XLogP	4.2	PubChem ↗
Topological polar surface area (Å²)	63.3	PubChem ↗
H-bond donors	1	PubChem ↗
H-bond acceptors	4	PubChem ↗
Rotatable bonds	5	PubChem ↗

PubChem computed values are shown separately from the ChEBI record. An exact InChIKey match was used to connect the records. Molecular descriptors do not describe a supplied product’s purity, particle size or performance.

Names & structural identifiers

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Source preferred name

oxaprozin

IUPAC name

3-(4,5-diphenyl-1,3-oxazol-2-yl)propanoic acid

InChIKey

OFPXSFXSNFPTHF-UHFFFAOYSA-N

SMILES

O=C(O)CCc1nc(-c2ccccc2)c(-c2ccccc2)o1

InChI

InChI=1S/C18H15NO3/c20-16(21)12-11-15-19-17(13-7-3-1-4-8-13)18(22-15)14-9-5-2-6-10-14/h1-10H,11-12H2,(H,20,21)

Names & synonyms

3-(4,5-diphenyl-1,3-oxazol-2-yl)propanoic acidDanoproxDayproDayrunDeflamDuraproxoxaprozinaoxaprozineoxaprozinumWalix

Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.

Classification & relationships

ChEBI ontology

monocarboxylic acidChEBI parent class · 25384 ↗1,3-oxazolesChEBI parent class · 46812 ↗

carboxylic acid organic heterocyclic compound organic molecular entity

Roles recorded in ChEBI

non-steroidal anti-inflammatory druganalgesicantirheumatic drug

Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.

Mass ↔ amount of substance

Calculated from sourced mass

Amount

Input unit

Equivalent amount

0.00340922 mol

Uses 293.322 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions

C

Carbon · 18 atoms

73.71%

O

Oxygen · 3 atoms

16.36%

H

Hydrogen · 15 atoms

5.15%

N

Nitrogen · 1 atom

4.78%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations

Oxaprozin: a new NSAID. ↗Orthopaedic review · 1992 May · PMID 1603605

Oxaprozin: a once-daily nonsteroidal anti-inflammatory drug. ↗Clinical pharmacy · 1992 Jul · PMID 1617910

FR2001036 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.

GB1206403 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.

US3578671 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.

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Sources & record history

Checked 27 Sep 2026

Identity, formula, mass, synonyms & ontologyEMBL-EBI ChEBI · CHEBI:7822

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

Additional molecular descriptorsNCBI PubChem · CID 4614 · retrieved 2026-09-27

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.

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