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Chemical substance record

Telbivudine

3424-98-4C10H14N2O5242.231 g/mol
Organic/Inorganic Small MoleculeChEBI source record

A pyrimidine 2'-deoxyribonucleoside that is the L-enantiomer of thymine. A synthetic thymidine nucleoside analogue with activity against HBV DNA polymerase. — ChEBI

Safety references

Safety documents & references

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Identity & molecular properties

Source-linked values
CAS number3424-98-4ChEBI ↗
Molecular formulaC10H14N2O5ChEBI ↗
Molar mass242.231 g/molChEBI ↗
Monoisotopic mass242.09027 DaChEBI ↗
Formal charge0ChEBI ↗
ChEBI identifierCHEBI:63624ChEBI ↗

Cross-source molecular data

PubChem
Molar mass242.23 g/molPubChem ↗
Exact mass242.09027155 DaPubChem ↗
Computed XLogP-1.2PubChem ↗
Topological polar surface area (Ų)99.1PubChem ↗
H-bond donors3PubChem ↗
H-bond acceptors5PubChem ↗
Rotatable bonds2PubChem ↗

PubChem computed values are shown separately from the ChEBI record. An exact InChIKey match was used to connect the records. Molecular descriptors do not describe a supplied product’s purity, particle size or performance.

Names & structural identifiers

Copy any identifier
telbivudine
1-(2-deoxy-beta-L-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione
IQFYYKKMVGJFEH-CSMHCCOUSA-N
Cc1cn([C@@H]2C[C@@H](O)[C@H](CO)O2)c(=O)nc1=O
InChI=1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m1/s1

Names & synonyms

1-(2-deoxy-beta-L-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione

Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.

Classification & relationships

ChEBI ontology
pyrimidine 2'-deoxyribonucleosideChEBI parent class · 19255 ↗
nucleosideorganic heterocyclic compoundorganic molecular entity

Roles recorded in ChEBI

antiviral agentantiviral drugEC 2.7.7.49 (RNA-directed DNA polymerase) inhibitorhepatoprotective agentanti-HBV agent

Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.

Mass ↔ amount of substance

Calculated from sourced mass
Equivalent amount
0.00412829 mol

Uses 242.231 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions
C
Carbon · 10 atoms
49.58%
O
Oxygen · 5 atoms
33.02%
N
Nitrogen · 2 atoms
11.56%
H
Hydrogen · 14 atoms
5.83%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations
Efficacy of switching to telbivudine in chronic hepatitis B patients treated previously with lamivudine. ↗Liver international : official journal of the International Association for the Study of the Liver · 2011 May · PMID 21040410
Significance of HBV DNA levels at 12 weeks of telbivudine treatment and the 3 years treatment outcome. ↗Journal of hepatology · 2011 Sep · PMID 21147187
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Sources & record history

Checked 27 Sep 2026
EMBL-EBI ChEBI · CHEBI:63624

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

NCBI PubChem · CID 159269 · retrieved 2026-09-27

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.

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