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Chemical substance record

Floxuridine

50-91-9C9H11FN2O5246.194 g/mol

A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract. — ChEBI

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Safety documents & references

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Identity & molecular properties

Source-linked values
CAS number50-91-9ChEBI ↗
Molecular formulaC9H11FN2O5ChEBI ↗
Molar mass246.194 g/molChEBI ↗
Monoisotopic mass246.0652 DaChEBI ↗
Formal charge0ChEBI ↗
ChEBI identifierCHEBI:60761ChEBI ↗

Cross-source molecular data

PubChem
Molar mass246.19 g/molPubChem ↗
Exact mass246.06519962 DaPubChem ↗
Computed XLogP-1.2PubChem ↗
Topological polar surface area (Ų)99.1PubChem ↗
H-bond donors3PubChem ↗
H-bond acceptors6PubChem ↗
Rotatable bonds2PubChem ↗

PubChem computed values are shown separately from the ChEBI record. An exact InChIKey match was used to connect the records. Molecular descriptors do not describe a supplied product’s purity, particle size or performance.

Names & structural identifiers

Copy any identifier
floxuridine
5-fluoro-2'-deoxyuridine
ODKNJVUHOIMIIZ-RRKCRQDMSA-N
O=c1nc(=O)n([C@H]2C[C@H](O)[C@@H](CO)O2)cc1F
InChI=1S/C9H11FN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1

Names & synonyms

5-fluoro-2'-deoxyuridinefloxiridinafloxuridinum

Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.

Classification & relationships

ChEBI ontology

Roles recorded in ChEBI

radiosensitizing agentantimetaboliteantineoplastic agentantiviral drug

Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.

Mass ↔ amount of substance

Calculated from sourced mass
Equivalent amount
0.00406184 mol

Uses 246.194 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions
C
Carbon · 9 atoms
43.91%
O
Oxygen · 5 atoms
32.49%
N
Nitrogen · 2 atoms
11.38%
F
Fluorine · 1 atom
7.72%
H
Hydrogen · 11 atoms
4.50%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations

Sources & record history

Checked 27 Sep 2026
EMBL-EBI ChEBI · CHEBI:60761

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

NCBI PubChem · CID 5790 · retrieved 2026-09-27

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.