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Chemical substance record

Kynurenic acid

492-27-3C10H7NO3189.17 g/mol

A quinolinemonocarboxylic acid that is quinoline-2-carboxylic acid substituted by a hydroxy group at C-4. — ChEBI

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Identity & molecular properties

Source-linked values
CAS number492-27-3ChEBI ↗
Molecular formulaC10H7NO3ChEBI ↗
Molar mass189.17 g/molChEBI ↗
Monoisotopic mass189.04259 DaChEBI ↗
Formal charge0ChEBI ↗
ChEBI identifierCHEBI:18344ChEBI ↗

Cross-source molecular data

PubChem
Molar mass189.17 g/molPubChem ↗
Exact mass189.042593085 DaPubChem ↗
Computed XLogP1.3PubChem ↗
Topological polar surface area (Ų)66.4PubChem ↗
H-bond donors2PubChem ↗
H-bond acceptors4PubChem ↗
Rotatable bonds1PubChem ↗

PubChem computed values are shown separately from the ChEBI record. An exact InChIKey match was used to connect the records. Molecular descriptors do not describe a supplied product’s purity, particle size or performance.

Names & structural identifiers

Copy any identifier
kynurenic acid
4-hydroxyquinoline-2-carboxylic acid
HCZHHEIFKROPDY-UHFFFAOYSA-N
O=C(O)c1cc(O)c2ccccc2n1
InChI=1S/C10H7NO3/c12-9-5-8(10(13)14)11-7-4-2-1-3-6(7)9/h1-5H,(H,11,12)(H,13,14)

Names & synonyms

4-hydroxyquinoline-2-carboxylic acid

Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.

Classification & relationships

ChEBI ontology

Roles recorded in ChEBI

nicotinic antagonistNMDA receptor antagonistneuroprotective agentG-protein-coupled receptor agonistSaccharomyces cerevisiae metabolitehuman metabolite

Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.

Mass ↔ amount of substance

Calculated from sourced mass
Equivalent amount
0.00528625 mol

Uses 189.17 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions
C
Carbon · 10 atoms
63.49%
O
Oxygen · 3 atoms
25.37%
N
Nitrogen · 1 atom
7.40%
H
Hydrogen · 7 atoms
3.73%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations
Effects of kynurenic acid as a glutamate receptor antagonist in the guinea pig. ↗European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2000 · PMID 10867830

Sources & record history

Checked 27 Sep 2026
EMBL-EBI ChEBI · CHEBI:18344

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

NCBI PubChem · CID 3845 · retrieved 2026-09-27

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.