Chemical substance record

Iodoquinol

83-73-8C₉H₅I₂NO396.953 g/mol

Organic/Inorganic Small MoleculeChEBI source record

A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by iodine. It is considered the drug of choice for treating asymptomatic or moderate forms of amoebiasis. — ChEBI

Safety references

Safety documents & references

Supplier matching matters

Find the safety document for your specific supplier, product number and grade.

Find a product-specific SDS

Search SDS PDFs Sigma-Aldrich Thermo Fisher

Safety guides and government classification records are not a manufacturer’s SDS. Match supplier, product number, concentration, physical form, region and revision before using a document.

Identity & molecular properties

Source-linked values

CAS number	83-73-8	ChEBI ↗
Molecular formula	C₉H₅I₂NO	ChEBI ↗
Molar mass	396.953 g/mol	ChEBI ↗
Monoisotopic mass	396.84606 Da	ChEBI ↗
Formal charge	0	ChEBI ↗
ChEBI identifier	CHEBI:5950	ChEBI ↗

Cross-source molecular data

PubChem

Molar mass	396.95 g/mol	PubChem ↗
Exact mass	396.84606 Da	PubChem ↗
Computed XLogP	3.1	PubChem ↗
Topological polar surface area (Å²)	33.1	PubChem ↗
H-bond donors	1	PubChem ↗
H-bond acceptors	2	PubChem ↗
Rotatable bonds	0	PubChem ↗

PubChem computed values are shown separately from the ChEBI record. An exact InChIKey match was used to connect the records. Molecular descriptors do not describe a supplied product’s purity, particle size or performance.

Names & structural identifiers

Copy any identifier

Source preferred name

iodoquinol

IUPAC name

5,7-diiodoquinolin-8-ol

InChIKey

UXZFQZANDVDGMM-UHFFFAOYSA-N

SMILES

Oc1c(I)cc(I)c2cccnc12

InChI

InChI=1S/C9H5I2NO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H

Names & synonyms

5,7-diiodoquinolin-8-olDiamoebindiiodohidroxiquinoleinadiiodohydroxyquinoleinediiodohydroxyquinolinediiodohydroxyquinolinumDiodoquineDiodoxylinDiquinolDirexiodeDyodinEmbequin

Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.

Classification & relationships

ChEBI ontology

organoiodine compoundChEBI parent class · 37142 ↗monohydroxyquinolineChEBI parent class · 38775 ↗

organic heterocyclic compound organic molecular entity

Roles recorded in ChEBI

antiamoebic agentantibacterial agentantiprotozoal drugantiseptic drug

Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.

Mass ↔ amount of substance

Calculated from sourced mass

Amount

Input unit

Equivalent amount

0.00251919 mol

Uses 396.953 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions

I

Iodine · 2 atoms

63.94%

C

Carbon · 9 atoms

27.23%

O

Oxygen · 1 atom

4.03%

N

Nitrogen · 1 atom

3.53%

H

Hydrogen · 5 atoms

1.27%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations

Letter: Diiodohydroxyquin and optic atrophy. ↗Pediatrics · 1975 Feb · PMID 1090898

Letter: Diiodohydroxyquin warning. ↗Journal of the Mississippi State Medical Association · 1975 Feb · PMID 122845

Search PubMed Google Scholar

Sources & record history

Checked 27 Sep 2026

Identity, formula, mass, synonyms & ontologyEMBL-EBI ChEBI · CHEBI:5950

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

Additional molecular descriptorsNCBI PubChem · CID 3728 · retrieved 2026-09-27

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.

How this record was assembled Suggest a correction