Chemical substance record

Buformin

692-13-7C₆H₁₅N₅157.221 g/mol

Organic/Inorganic Small MoleculeChEBI source record

A member of the class of biguanides that is biguanide substituted by a butyl group at position 1. It is an antidiabetic drug with potential antitumor effect. — ChEBI

Safety references

Safety documents & references

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Identity & molecular properties

Source-linked values

CAS number	692-13-7	ChEBI ↗
Molecular formula	C₆H₁₅N₅	ChEBI ↗
Molar mass	157.221 g/mol	ChEBI ↗
Monoisotopic mass	157.13275 Da	ChEBI ↗
Formal charge	0	ChEBI ↗
ChEBI identifier	CHEBI:3209	ChEBI ↗

Cross-source molecular data

PubChem

Molar mass	157.22 g/mol	PubChem ↗
Exact mass	157.13274550 Da	PubChem ↗
Computed XLogP	-0.6	PubChem ↗
Topological polar surface area (Å²)	103	PubChem ↗
H-bond donors	3	PubChem ↗
H-bond acceptors	1	PubChem ↗
Rotatable bonds	4	PubChem ↗

PubChem computed values are shown separately from the ChEBI record. An exact InChIKey match was used to connect the records. Molecular descriptors do not describe a supplied product’s purity, particle size or performance.

Names & structural identifiers

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Source preferred name

buformin

IUPAC name

N-butyltriimidodicarbonic diamide

InChIKey

XSEUMFJMFFMCIU-UHFFFAOYSA-N

SMILES

CCCCNC(=N)NC(=N)N

InChI

InChI=1S/C6H15N5/c1-2-3-4-10-6(9)11-5(7)8/h2-4H2,1H3,(H6,7,8,9,10,11)

Names & synonyms

buforminabuforminebuforminumN-butyltriimidodicarbonic diamide

Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.

Classification & relationships

ChEBI ontology

biguanidesChEBI parent class · 53662 ↗

organic molecular entity

Roles recorded in ChEBI

radiosensitizing agentgeroprotectorantiviral agenthypoglycemic agentantineoplastic agent

Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.

Mass ↔ amount of substance

Calculated from sourced mass

Amount

Input unit

Equivalent amount

0.00636047 mol

Uses 157.221 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions

C

Carbon · 6 atoms

45.84%

N

Nitrogen · 5 atoms

44.55%

H

Hydrogen · 15 atoms

9.62%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations

Acrylic microspheres for oral controlled release of the biguanide buformin. ↗International journal of pharmaceutics · 2001 May 7 · PMID 11337146

A new method for determination of buformin in plasma and urine by ion-paired reversed-phase HPLC with ultraviolet detection. ↗Biomedical chromatography : BMC · 2002 Oct · PMID 12378556

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Sources & record history

Checked 27 Sep 2026

Identity, formula, mass, synonyms & ontologyEMBL-EBI ChEBI · CHEBI:3209

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

Additional molecular descriptorsNCBI PubChem · CID 2468 · retrieved 2026-09-27

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.

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