Chemical substance record

Ofloxacin

82419-36-1C₁₈H₂₀FN₃O₄361.373 g/mol

Organic/Inorganic Small MoleculeChEBI source record

A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication. — ChEBI

Safety references

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Identity & molecular properties

Source-linked values

CAS number	82419-36-1	ChEBI ↗
Molecular formula	C₁₈H₂₀FN₃O₄	ChEBI ↗
Molar mass	361.373 g/mol	ChEBI ↗
Monoisotopic mass	361.14378 Da	ChEBI ↗
Formal charge	0	ChEBI ↗
ChEBI identifier	CHEBI:7731	ChEBI ↗

Names & structural identifiers

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Source preferred name

ofloxacin

IUPAC name

rac-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid

Names & synonyms

ExocinFloxinGailuoxianOcufloxofloxacineofloxacinoofloxacinumOxaldinPrifloxcinPrifloxinrac-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acidTarivid

Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.

Classification & relationships

ChEBI ontology

racemateChEBI parent class · 60911 ↗quinolone antibioticChEBI parent class · 86324 ↗fluoroquinolone antibioticChEBI parent class · 87211 ↗

organofluorine compound organic heterocyclic compound organic molecular entity

Roles recorded in ChEBI

antibacterial agentantiinfective agentantihypertensive agentantibacterial drugantiglaucoma druganti-ulcer drugEC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitortopoisomerase IV inhibitorDNA synthesis inhibitorophthalmology drug

Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.

Mass ↔ amount of substance

Calculated from sourced mass

Amount

Input unit

Equivalent amount

0.00276722 mol

Uses 361.373 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions

C

Carbon · 18 atoms

59.83%

O

Oxygen · 4 atoms

17.71%

N

Nitrogen · 3 atoms

11.63%

H

Hydrogen · 20 atoms

5.58%

F

Fluorine · 1 atom

5.26%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations

Quinolone-photoconjugated major histocompatibility complex class II-binding peptides with lysine are antigenic for T cells mediating murine quinolone photoallergy. ↗The Journal of investigative dermatology · 2001 Nov · PMID 11710934

Inhibition of rat parotid and submandibular gland functions by ofloxacin, a fluoroquinolone antibiotic. ↗Fundamental & clinical pharmacology · 2001 Oct · PMID 11903499

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Sources & record history

Checked 27 Sep 2026

Identity, formula, mass, synonyms & ontologyEMBL-EBI ChEBI · CHEBI:7731

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.

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