Chemical substance record

Risperidone

106266-06-2C₂₃H₂₇FN₄O₂410.493 g/mol

Organic/Inorganic Small MoleculeChEBI source record

A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2. — ChEBI

Safety references

Safety documents & references

Supplier matching matters

Find the safety document for your specific supplier, product number and grade.

Find a product-specific SDS

Search SDS PDFs Sigma-Aldrich Thermo Fisher

Safety guides and government classification records are not a manufacturer’s SDS. Match supplier, product number, concentration, physical form, region and revision before using a document.

Identity & molecular properties

Source-linked values

CAS number	106266-06-2	ChEBI ↗
Molecular formula	C₂₃H₂₇FN₄O₂	ChEBI ↗
Molar mass	410.493 g/mol	ChEBI ↗
Monoisotopic mass	410.2118 Da	ChEBI ↗
Formal charge	0	ChEBI ↗
ChEBI identifier	CHEBI:8871	ChEBI ↗

Cross-source molecular data

PubChem

Molar mass	410.5 g/mol	PubChem ↗
Exact mass	410.21180428 Da	PubChem ↗
Computed XLogP	2.7	PubChem ↗
Topological polar surface area (Å²)	61.9	PubChem ↗
H-bond donors	0	PubChem ↗
H-bond acceptors	6	PubChem ↗
Rotatable bonds	4	PubChem ↗

PubChem computed values are shown separately from the ChEBI record. An exact InChIKey match was used to connect the records. Molecular descriptors do not describe a supplied product’s purity, particle size or performance.

Names & structural identifiers

Copy any identifier

Source preferred name

risperidone

IUPAC name

3-{2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)piperidin-1-yl]ethyl}-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one

InChIKey

RAPZEAPATHNIPO-UHFFFAOYSA-N

SMILES

Cc1nc2n(c(=O)c1CCN1CCC(c3noc4cc(F)ccc34)CC1)CCCC2

InChI

InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3

Names & synonyms

3-{2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)piperidin-1-yl]ethyl}-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-oneRisperdalrisperidonarisperidonumRisperinRispoleptRispolinSequinan

Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.

Classification & relationships

ChEBI ontology

organofluorine compoundChEBI parent class · 37143 ↗pyridopyrimidineChEBI parent class · 38932 ↗heteroarylpiperidineChEBI parent class · 48585 ↗1,2-benzoxazolesChEBI parent class · 51545 ↗

organofluorine compound organic heterocyclic compound organic molecular entity

Roles recorded in ChEBI

antidepressantpsychotropic druganxiolytic drugalpha-adrenergic antagonistH1-receptor antagonistserotonergic antagonistdopaminergic antagonistsecond generation antipsychoticEC 3.4.21.26 (prolyl oligopeptidase) inhibitor

Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.

Mass ↔ amount of substance

Calculated from sourced mass

Amount

Input unit

Equivalent amount

0.0024361 mol

Uses 410.493 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions

C

Carbon · 23 atoms

67.30%

N

Nitrogen · 4 atoms

13.65%

O

Oxygen · 2 atoms

7.80%

H

Hydrogen · 27 atoms

6.63%

F

Fluorine · 1 atom

4.63%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations

Acute and long-term treatment of catatonia with risperidone. ↗Pharmacopsychiatry · 2001 Jan · PMID 11229618

An evaluation of risperidone drug interactions. ↗Journal of clinical psychopharmacology · 2001 Aug · PMID 11476125

EP196132 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.

US4804663 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.

Search PubMed Google Scholar

Sources & record history

Checked 27 Sep 2026

Identity, formula, mass, synonyms & ontologyEMBL-EBI ChEBI · CHEBI:8871

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

Additional molecular descriptorsNCBI PubChem · CID 5073 · retrieved 2026-09-27

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.

How this record was assembled Suggest a correction