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Chemical substance record

Ethylene glycol

107-21-1C2H6O262.068 g/mol

A 1,2-glycol compound produced via reaction of ethylene oxide with water. — ChEBI

Safety references

Safety documents & references

2 indexed references
US · NIOSH

Occupational chemical safety guide

Ethylene glycol

Read official guide
JP · NITE

Government GHS classification

H26-B-017 / R-061 · FY2014

View classification

Find a product-specific SDS

Safety guides and government classification records are not a manufacturer’s SDS. Match supplier, product number, concentration, physical form, region and revision before using a document.

Identity & molecular properties

Source-linked values
CAS number107-21-1ChEBI ↗
Molecular formulaC2H6O2ChEBI ↗
Molar mass62.068 g/molChEBI ↗
Monoisotopic mass62.03678 DaChEBI ↗
Formal charge0ChEBI ↗
ChEBI identifierCHEBI:30742ChEBI ↗

Cross-source molecular data

PubChem
Molar mass62.07 g/molPubChem ↗
Exact mass62.036779430 DaPubChem ↗
Computed XLogP-1.4PubChem ↗
Topological polar surface area (Ų)40.5PubChem ↗
H-bond donors2PubChem ↗
H-bond acceptors2PubChem ↗
Rotatable bonds1PubChem ↗

PubChem computed values are shown separately from the ChEBI record. An exact InChIKey match was used to connect the records. Molecular descriptors do not describe a supplied product’s purity, particle size or performance.

Names & structural identifiers

Copy any identifier
ethylene glycol
ethane-1,2-diol
LYCAIKOWRPUZTN-UHFFFAOYSA-N
OCCO
InChI=1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

Names & synonyms

ethane-1,2-diol

Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.

Classification & relationships

ChEBI ontology

Roles recorded in ChEBI

metabolitetoxinsolventmouse metabolite

Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.

Safety classification · Japan

NITE / Japanese government
Japan · FY2014 source classification
Ethylene glycol · H26-B-017 / R-061
EndpointReported classification
Acute toxicity (Inhalation: Dusts and mists)Category 4
Skin corrosion/irritationCategory 2
Serious eye damage/eye irritationCategory 2B
Specific target organ toxicity - Single exposureCategory 1 (central nervous system, blood system, kidney), Category 3 (respiratory tract irritation, narcotic effects)

Selected source-reported endpoints. Other endpoints, rationales and conditions remain in the original classification. Missing or unlisted information does not mean non-hazardous. This is not a global classification or transport decision.

Read the original NITE classification

Mass ↔ amount of substance

Calculated from sourced mass
Equivalent amount
0.0161114 mol

Uses 62.068 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions
O
Oxygen · 2 atoms
51.55%
C
Carbon · 2 atoms
38.70%
H
Hydrogen · 6 atoms
9.74%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations
Novel therapies for ethylene glycol intoxication. ↗Current opinion in pediatrics · 1999 Jun · PMID 10349109
Development of a physiologically based pharmacokinetic model for ethylene glycol and its metabolite, glycolic Acid, in rats and humans. ↗Toxicological sciences : an official journal of the Society of Toxicology · 2005 May · PMID 15716482

Sources & record history

Checked 27 Sep 2026
EMBL-EBI ChEBI · CHEBI:30742

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

NCBI PubChem · CID 174 · retrieved 2026-09-27

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.