Chemical substance record

Flunixin

38677-85-9C₁₄H₁₁F₃N₂O₂296.248 g/mol

Organic/Inorganic Small MoleculeChEBI source record

A pyridinemonocarboxylic acid that is nicotinic acid substituted at position 2 by a 2-methyl-3-(trifluoromethyl)phenylamino group. A relatively potent non-narcotic, nonsteroidal analgesic with anti-inflammatory, anti-endotoxic and anti-pyretic properties; used in veterinary medicine (usually as the meglumine salt) for treatment of horses, cattle and pigs. — ChEBI

Safety references

Safety documents & references

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Identity & molecular properties

Source-linked values

CAS number	38677-85-9	ChEBI ↗
Molecular formula	C₁₄H₁₁F₃N₂O₂	ChEBI ↗
Molar mass	296.248 g/mol	ChEBI ↗
Monoisotopic mass	296.07726 Da	ChEBI ↗
Formal charge	0	ChEBI ↗
ChEBI identifier	CHEBI:76138	ChEBI ↗

Cross-source molecular data

PubChem

Molar mass	296.24 g/mol	PubChem ↗
Exact mass	296.07726208 Da	PubChem ↗
Computed XLogP	4.1	PubChem ↗
Topological polar surface area (Å²)	62.2	PubChem ↗
H-bond donors	2	PubChem ↗
H-bond acceptors	7	PubChem ↗
Rotatable bonds	3	PubChem ↗

PubChem computed values are shown separately from the ChEBI record. An exact InChIKey match was used to connect the records. Molecular descriptors do not describe a supplied product’s purity, particle size or performance.

Names & structural identifiers

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Source preferred name

flunixin

IUPAC name

2-{[2-methyl-3-(trifluoromethyl)phenyl]amino}nicotinic acid

InChIKey

NOOCSNJCXJYGPE-UHFFFAOYSA-N

SMILES

Cc1c(Nc2ncccc2C(=O)O)cccc1C(F)(F)F

InChI

InChI=1S/C14H11F3N2O2/c1-8-10(14(15,16)17)5-2-6-11(8)19-12-9(13(20)21)4-3-7-18-12/h2-7H,1H3,(H,18,19)(H,20,21)

Names & synonyms

2-{[2-methyl-3-(trifluoromethyl)phenyl]amino}nicotinic acidflunixineflunixinoflunixinum

Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.

Classification & relationships

ChEBI ontology

pyridinemonocarboxylic acidChEBI parent class · 26420 ↗organofluorine compoundChEBI parent class · 37143 ↗aminopyridineChEBI parent class · 38207 ↗

carboxylic acid organofluorine compound organic heterocyclic compound organic molecular entity

Roles recorded in ChEBI

non-steroidal anti-inflammatory drugnon-narcotic analgesicantipyreticEC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor

Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.

Mass ↔ amount of substance

Calculated from sourced mass

Amount

Input unit

Equivalent amount

0.00337555 mol

Uses 296.248 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions

C

Carbon · 14 atoms

56.76%

F

Fluorine · 3 atoms

19.24%

O

Oxygen · 2 atoms

10.80%

N

Nitrogen · 2 atoms

9.46%

H

Hydrogen · 11 atoms

3.74%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations

The Safety and Pharmacokinetics of Carprofen, Flunixin and Phenylbutazone in the Cape Vulture (Gyps coprotheres) following Oral Exposure. ↗PloS one · 2015 · PMID 26512724

Screening and Confirmatory Analyses of Flunixin in Tissues and Bodily Fluids after Intravenous or Intramuscular Administration to Cull Dairy Cows with or without Lipopolysaccharide Challenge. ↗Journal of agricultural and food chemistry · 2016 Jan 13 · PMID 26695354

US2008014272 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.

US5637617 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.

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Sources & record history

Checked 27 Sep 2026

Identity, formula, mass, synonyms & ontologyEMBL-EBI ChEBI · CHEBI:76138

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

Additional molecular descriptorsNCBI PubChem · CID 38081 · retrieved 2026-09-27

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.

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