Chemical substance record

Methamphetamine

537-46-2C₁₀H₁₅N149.237 g/mol

Organic/Inorganic Small MoleculeChEBI source record

A member of the class of amphetamines in which the amino group of (S)-amphetamine carries a methyl substituent. — ChEBI

Safety references

Safety documents & references

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Identity & molecular properties

Source-linked values

CAS number	537-46-2	ChEBI ↗
Molecular formula	C₁₀H₁₅N	ChEBI ↗
Molar mass	149.237 g/mol	ChEBI ↗
Monoisotopic mass	149.12045 Da	ChEBI ↗
Formal charge	0	ChEBI ↗
ChEBI identifier	CHEBI:6809	ChEBI ↗

Cross-source molecular data

PubChem

Molar mass	149.23 g/mol	PubChem ↗
Exact mass	149.120449483 Da	PubChem ↗
Computed XLogP	2.1	PubChem ↗
Topological polar surface area (Å²)	12	PubChem ↗
H-bond donors	1	PubChem ↗
H-bond acceptors	1	PubChem ↗
Rotatable bonds	3	PubChem ↗

PubChem computed values are shown separately from the ChEBI record. An exact InChIKey match was used to connect the records. Molecular descriptors do not describe a supplied product’s purity, particle size or performance.

Names & structural identifiers

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Source preferred name

methamphetamine

IUPAC name

(2S)-N-methyl-1-phenylpropan-2-amine

InChIKey

MYWUZJCMWCOHBA-VIFPVBQESA-N

SMILES

CN[C@@H](C)Cc1ccccc1

InChI

InChI=1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3/t9-/m0/s1

Names & synonyms

(2S)-N-methyl-1-phenylpropan-2-aminemetamfetaminemetamfetaminummetanfetamina

Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.

Classification & relationships

ChEBI ontology

secondary amineChEBI parent class · 32863 ↗amphetaminesChEBI parent class · 35338 ↗

amine organic molecular entity

Roles recorded in ChEBI

central nervous system stimulantpsychotropic drugxenobioticneurotoxinenvironmental contaminant

Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.

Mass ↔ amount of substance

Calculated from sourced mass

Amount

Input unit

Equivalent amount

0.00670075 mol

Uses 149.237 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions

C

Carbon · 10 atoms

80.48%

H

Hydrogen · 15 atoms

10.13%

N

Nitrogen · 1 atom

9.39%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations

Methamphetamine use: hazards and social influences. ↗Journal of drug education · 2000 · PMID 11221576

Methamphetamine increases expression of the apoptotic c-myc and L-myc genes in the mouse brain. ↗Brain research. Molecular brain research · 2001 Jun 20 · PMID 11406298

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Sources & record history

Checked 27 Sep 2026

Identity, formula, mass, synonyms & ontologyEMBL-EBI ChEBI · CHEBI:6809

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

Additional molecular descriptorsNCBI PubChem · CID 10836 · retrieved 2026-09-27

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.

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