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Chemical substance record

Clofibrate

637-07-0C12H15ClO3242.702 g/mol
Organic/Inorganic Small MoleculeChEBI source record

The ethyl ester of clofibric acid. — ChEBI

Safety references

Safety documents & references

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Identity & molecular properties

Source-linked values
CAS number637-07-0ChEBI ↗
Molecular formulaC12H15ClO3ChEBI ↗
Molar mass242.702 g/molChEBI ↗
Monoisotopic mass242.07097 DaChEBI ↗
Formal charge0ChEBI ↗
ChEBI identifierCHEBI:3750ChEBI ↗

Cross-source molecular data

PubChem
Molar mass242.70 g/molPubChem ↗
Exact mass242.0709720 DaPubChem ↗
Computed XLogP3.3PubChem ↗
Topological polar surface area (Ų)35.5PubChem ↗
H-bond donors0PubChem ↗
H-bond acceptors3PubChem ↗
Rotatable bonds5PubChem ↗

PubChem computed values are shown separately from the ChEBI record. An exact InChIKey match was used to connect the records. Molecular descriptors do not describe a supplied product’s purity, particle size or performance.

Names & structural identifiers

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clofibrate
ethyl 2-(4-chlorophenoxy)-2-methylpropanoate
KNHUKKLJHYUCFP-UHFFFAOYSA-N
CCOC(=O)C(C)(C)Oc1ccc(Cl)cc1
InChI=1S/C12H15ClO3/c1-4-15-11(14)12(2,3)16-10-7-5-9(13)6-8-10/h5-8H,4H2,1-3H3

Names & synonyms

Atromid-SclofibratoclofibratumELPIethyl 2-(4-chlorophenoxy)-2-methylpropanoateLipofacton

Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.

Classification & relationships

ChEBI ontology
ethyl esterChEBI parent class · 23990 ↗aromatic etherChEBI parent class · 35618 ↗monochlorobenzenesChEBI parent class · 83403 ↗
esteretherorganochlorine compoundorganic molecular entity

Roles recorded in ChEBI

geroprotectorcardiovascular drugantilipemic druganticholesteremic drugPPARalpha agonist

Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.

Mass ↔ amount of substance

Calculated from sourced mass
Equivalent amount
0.00412028 mol

Uses 242.702 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions
C
Carbon · 12 atoms
59.39%
O
Oxygen · 3 atoms
19.78%
Cl
Chlorine · 1 atom
14.61%
H
Hydrogen · 15 atoms
6.23%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations
Lipid-lowering fibrates extend C. elegans lifespan in a NHR-49/PPARalpha-dependent manner. ↗Aging · 2013 Apr · PMID 23603800
Effect of clofibrate on fatty acid metabolism in the kidney of puromycin-induced nephrotic rats. ↗Clinical and experimental nephrology · 2016 Dec · PMID 26949064
GB860303 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.
US3262850 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.
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Sources & record history

Checked 27 Sep 2026
EMBL-EBI ChEBI · CHEBI:3750

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

NCBI PubChem · CID 2796 · retrieved 2026-09-27

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.

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