Chemical substance record

Bicalutamide

90357-06-5C₁₈H₁₄F₄N₂O₄S430.379 g/mol

Organic/Inorganic Small MoleculeChEBI source record

A racemate comprising of equal amounts of (R)-bicalutamide and (S)-bicalutamide. It is an oral non-steroidal antiandrogen used in the treatment of prostate cancer and hirsutism. — ChEBI

Safety references

Safety documents & references

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Identity & molecular properties

Source-linked values

CAS number	90357-06-5	ChEBI ↗
Molecular formula	C₁₈H₁₄F₄N₂O₄S	ChEBI ↗
Molar mass	430.379 g/mol	ChEBI ↗
Monoisotopic mass	430.06104 Da	ChEBI ↗
Formal charge	0	ChEBI ↗
ChEBI identifier	CHEBI:3090	ChEBI ↗

Names & structural identifiers

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Source preferred name

bicalutamide

IUPAC name

rac-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide

Names & synonyms

BicadexBicalBicaloxbicalutamidabicalutamidumBicamideBicatlonBicusanBinabicByproCalumidCalutide

Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.

Classification & relationships

ChEBI ontology

racemateChEBI parent class · 60911 ↗

Roles recorded in ChEBI

antiviral agentandrogen antagonistantineoplastic agentxenobioticenvironmental contaminant

Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.

Mass ↔ amount of substance

Calculated from sourced mass

Amount

Input unit

Equivalent amount

0.00232353 mol

Uses 430.379 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions

C

Carbon · 18 atoms

50.23%

F

Fluorine · 4 atoms

17.66%

O

Oxygen · 4 atoms

14.87%

S

Sulfur · 1 atom

7.45%

N

Nitrogen · 2 atoms

6.51%

H

Hydrogen · 14 atoms

3.28%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations

New alternative treatment in hirsutism: bicalutamide 25 mg/day. ↗Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2002 Feb · PMID 11915584

Bicalutamide functions as an androgen receptor antagonist by assembly of a transcriptionally inactive receptor. ↗The Journal of biological chemistry · 2002 Jul 19 · PMID 12015321

EP100172 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.

US4636505 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.

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Sources & record history

Checked 27 Sep 2026

Identity, formula, mass, synonyms & ontologyEMBL-EBI ChEBI · CHEBI:3090

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.

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