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Chemical substance record

Tolfenamic acid

13710-19-5C14H12ClNO2261.708 g/mol

An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 3-chloro-2-methylphenyl group. Tolfenamic acid is used specifically for relieving the pain of migraine. It also shows anticancer activity. — ChEBI

Safety references

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Identity & molecular properties

Source-linked values
CAS number13710-19-5ChEBI ↗
Molecular formulaC14H12ClNO2ChEBI ↗
Molar mass261.708 g/molChEBI ↗
Monoisotopic mass261.05566 DaChEBI ↗
Formal charge0ChEBI ↗
ChEBI identifierCHEBI:32243ChEBI ↗

Cross-source molecular data

PubChem
Molar mass261.70 g/molPubChem ↗
Exact mass261.0556563 DaPubChem ↗
Computed XLogP5.2PubChem ↗
Topological polar surface area (Ų)49.3PubChem ↗
H-bond donors2PubChem ↗
H-bond acceptors3PubChem ↗
Rotatable bonds3PubChem ↗

PubChem computed values are shown separately from the ChEBI record. An exact InChIKey match was used to connect the records. Molecular descriptors do not describe a supplied product’s purity, particle size or performance.

Names & structural identifiers

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tolfenamic acid
2-[(3-chloro-2-methylphenyl)amino]benzoic acid
YEZNLOUZAIOMLT-UHFFFAOYSA-N
Cc1c(Cl)cccc1Nc1ccccc1C(=O)O
InChI=1S/C14H12ClNO2/c1-9-11(15)6-4-8-12(9)16-13-7-3-2-5-10(13)14(17)18/h2-8,16H,1H3,(H,17,18)

Names & synonyms

2-[(3-chloro-2-methylphenyl)amino]benzoic acidacide tolfenamiqueacido tolfenamicoacidum tolfenamicum

Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.

Classification & relationships

ChEBI ontology

Roles recorded in ChEBI

non-steroidal anti-inflammatory drugnon-narcotic analgesicEC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitorantineoplastic agentEC 2.7.1.33 (pantothenate kinase) inhibitor

Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.

Mass ↔ amount of substance

Calculated from sourced mass
Equivalent amount
0.00382105 mol

Uses 261.708 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions
C
Carbon · 14 atoms
64.25%
Cl
Chlorine · 1 atom
13.55%
O
Oxygen · 2 atoms
12.23%
N
Nitrogen · 1 atom
5.35%
H
Hydrogen · 12 atoms
4.62%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations

Sources & record history

Checked 27 Sep 2026
EMBL-EBI ChEBI · CHEBI:32243

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

NCBI PubChem · CID 610479 · retrieved 2026-09-27

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.