Chemical substance record

Ferrostatin-1

347174-05-4C₁₅H₂₂N₂O₂262.353 g/mol

Organic/Inorganic Small MoleculeChEBI source record

An ethyl ester resulting from the formal condensation of the carboxy group of 3-amino-4-(cyclohexylamino)benzoic acid with ethanol. It is a potent inhibitor of ferroptosis, a distinct non-apoptotic form of cell death caused by lipid peroxidation. It is also a radical-trapping antioxidant and has the ability to reduce the accumulation of lipid peroxides and chain-carrying peroxyl radicals. — ChEBI

Safety references

Safety documents & references

Supplier matching matters

Find the safety document for your specific supplier, product number and grade.

Find a product-specific SDS

Search SDS PDFs Sigma-Aldrich Thermo Fisher

Safety guides and government classification records are not a manufacturer’s SDS. Match supplier, product number, concentration, physical form, region and revision before using a document.

Identity & molecular properties

Source-linked values

CAS number	347174-05-4	ChEBI ↗
Molecular formula	C₁₅H₂₂N₂O₂	ChEBI ↗
Molar mass	262.353 g/mol	ChEBI ↗
Monoisotopic mass	262.16813 Da	ChEBI ↗
Formal charge	0	ChEBI ↗
ChEBI identifier	CHEBI:173086	ChEBI ↗

Names & structural identifiers

Copy any identifier

Source preferred name

ferrostatin-1

IUPAC name

ethyl 3-amino-4-(cyclohexylamino)benzoate

InChIKey

UJHBVMHOBZBWMX-UHFFFAOYSA-N

SMILES

CCOC(=O)c1ccc(NC2CCCCC2)c(N)c1

InChI

InChI=1S/C15H22N2O2/c1-2-19-15(18)11-8-9-14(13(16)10-11)17-12-6-4-3-5-7-12/h8-10,12,17H,2-7,16H2,1H3

Names & synonyms

ethyl 3-amino-4-(cyclohexylamino)benzoate

Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.

Classification & relationships

ChEBI ontology

ethyl esterChEBI parent class · 23990 ↗substituted anilineChEBI parent class · 48975 ↗primary arylamineChEBI parent class · 50471 ↗

amine ester organic molecular entity

Roles recorded in ChEBI

ferroptosis inhibitorantioxidantantifungal agentradical scavengerneuroprotective agentradiation protective agent

Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.

Mass ↔ amount of substance

Calculated from sourced mass

Amount

Input unit

Equivalent amount

0.00381166 mol

Uses 262.353 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions

C

Carbon · 15 atoms

68.67%

O

Oxygen · 2 atoms

12.20%

N

Nitrogen · 2 atoms

10.68%

H

Hydrogen · 22 atoms

8.45%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations

Ferroptosis: an iron-dependent form of nonapoptotic cell death. ↗Cell · 2012 May 25 · PMID 22632970

The neuroprotective role of ferrostatin-1 under rotenone-induced oxidative stress in dopaminergic neuroblastoma cells. ↗The protein journal · 2015 Oct · PMID 26385697

Search PubMed Google Scholar

Sources & record history

Checked 27 Sep 2026

Identity, formula, mass, synonyms & ontologyEMBL-EBI ChEBI · CHEBI:173086

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.

How this record was assembled Suggest a correction