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Chemical substance record

Tetracaine

94-24-6C15H24N2O2264.369 g/mol
Organic/Inorganic Small MoleculeChEBI source record

A benzoate ester in which 4-N-butylbenzoic acid and 2-(dimethylamino)ethanol have combined to form the ester bond; a local ester anaesthetic (ester caine) used for surface and spinal anaesthesia. — ChEBI

Safety references

Safety documents & references

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Identity & molecular properties

Source-linked values
CAS number94-24-6ChEBI ↗
Molecular formulaC15H24N2O2ChEBI ↗
Molar mass264.369 g/molChEBI ↗
Monoisotopic mass264.18378 DaChEBI ↗
Formal charge0ChEBI ↗
ChEBI identifierCHEBI:9468ChEBI ↗

Cross-source molecular data

PubChem
Molar mass264.36 g/molPubChem ↗
Exact mass264.183778013 DaPubChem ↗
Computed XLogP3.7PubChem ↗
Topological polar surface area (Ų)41.6PubChem ↗
H-bond donors1PubChem ↗
H-bond acceptors4PubChem ↗
Rotatable bonds9PubChem ↗

PubChem computed values are shown separately from the ChEBI record. An exact InChIKey match was used to connect the records. Molecular descriptors do not describe a supplied product’s purity, particle size or performance.

Names & structural identifiers

Copy any identifier
tetracaine
2-(dimethylamino)ethyl 4-(butylamino)benzoate
GKCBAIGFKIBETG-UHFFFAOYSA-N
CCCCNc1ccc(C(=O)OCCN(C)C)cc1
InChI=1S/C15H24N2O2/c1-4-5-10-16-14-8-6-13(7-9-14)15(18)19-12-11-17(2)3/h6-9,16H,4-5,10-12H2,1-3H3

Names & synonyms

2-(dimethylamino)ethyl 4-(butylamino)benzoateAmethocainetetracainatetracainum

Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.

Classification & relationships

ChEBI ontology
benzoate esterChEBI parent class · 36054 ↗tertiary amino compoundChEBI parent class · 50996 ↗
esterorganic molecular entity

Roles recorded in ChEBI

analgesiclocal anaestheticophthalmology druganti-inflammatory agentvulnerary

Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.

Mass ↔ amount of substance

Calculated from sourced mass
Equivalent amount
0.00378259 mol

Uses 264.369 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions
C
Carbon · 15 atoms
68.15%
O
Oxygen · 2 atoms
12.10%
N
Nitrogen · 2 atoms
10.60%
H
Hydrogen · 24 atoms
9.15%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations
Tetracaine, a local anesthetic, preferentially induces translational inhibition with processing body formation rather than phosphorylation of eIF2α in yeast. ↗Current genetics · 2015 Feb · PMID 25119673
Intranasal anesthetic effects of lidocaine and tetracaine compared. ↗Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 1995 Oct · PMID 7567006
US1889645 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.
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Sources & record history

Checked 27 Sep 2026
EMBL-EBI ChEBI · CHEBI:9468

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

NCBI PubChem · CID 5411 · retrieved 2026-09-27

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.

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