Skip to content
[P]pubcas
Independent chemical reference Compare
Chemical substance record

Chloramphenicol

56-75-7C11H12Cl2N2O5323.132 g/mol

An organochlorine compound that is dichloro-substituted acetamide containing a nitrobenzene ring, an amide bond and two alcohol functions. — ChEBI

Safety references

Safety documents & references

1 indexed references
JP · NITE

Government GHS classification

R02-B-069-MHLW, MOE · FY2020

View classification

Find a product-specific SDS

Safety guides and government classification records are not a manufacturer’s SDS. Match supplier, product number, concentration, physical form, region and revision before using a document.

Identity & molecular properties

Source-linked values
CAS number56-75-7ChEBI ↗
Molecular formulaC11H12Cl2N2O5ChEBI ↗
Molar mass323.132 g/molChEBI ↗
Monoisotopic mass322.01233 DaChEBI ↗
Formal charge0ChEBI ↗
ChEBI identifierCHEBI:17698ChEBI ↗

Cross-source molecular data

PubChem
Molar mass323.13 g/molPubChem ↗
Exact mass322.0123269 DaPubChem ↗
Computed XLogP1.1PubChem ↗
Topological polar surface area (Ų)115PubChem ↗
H-bond donors3PubChem ↗
H-bond acceptors5PubChem ↗
Rotatable bonds5PubChem ↗

PubChem computed values are shown separately from the ChEBI record. An exact InChIKey match was used to connect the records. Molecular descriptors do not describe a supplied product’s purity, particle size or performance.

Names & structural identifiers

Copy any identifier
chloramphenicol
2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide
WIIZWVCIJKGZOK-RKDXNWHRSA-N
O=C(N[C@H](CO)[C@H](O)c1ccc([N+](=O)[O-])cc1)C(Cl)Cl
InChI=1S/C11H12Cl2N2O5/c12-10(13)11(18)14-8(5-16)9(17)6-1-3-7(4-2-6)15(19)20/h1-4,8-10,16-17H,5H2,(H,14,18)/t8-,9-/m1/s1

Names & synonyms

2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamideAmphicolChloramexchloramphenicolumChlorocidChlorocolChloromycetincloramfenicolEconochlorFenicolGlobenicolHalomycetin

Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.

Classification & relationships

ChEBI ontology

Roles recorded in ChEBI

Mycoplasma genitalium metabolitegeroprotectorantimicrobial agentantibacterial agentantibacterial drugprotein synthesis inhibitorophthalmology drugEscherichia coli metabolite

Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.

Safety classification · Japan

NITE / Japanese government
Japan · FY2020 source classification
2,2-Dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide; Chloramphenicol · R02-B-069-MHLW, MOE
EndpointReported classification
Germ cell mutagenicityCategory 2
CarcinogenicityCategory 1B
Reproductive toxicityCategory 1B
Specific target organ toxicity - Repeated exposureCategory 1 (hematopoietic system, nervous system, circulatory system, digestive organ)
Hazardous to the aquatic environment (Acute)Category 1
Hazardous to the aquatic environment (Long-term)Category 1

Selected source-reported endpoints. Other endpoints, rationales and conditions remain in the original classification. Missing or unlisted information does not mean non-hazardous. This is not a global classification or transport decision.

Read the original NITE classification

Mass ↔ amount of substance

Calculated from sourced mass
Equivalent amount
0.00309471 mol

Uses 323.132 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions
C
Carbon · 11 atoms
40.89%
O
Oxygen · 5 atoms
24.76%
Cl
Chlorine · 2 atoms
21.94%
N
Nitrogen · 2 atoms
8.67%
H
Hydrogen · 12 atoms
3.74%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations
GB795131 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.
GB796901 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.
US2483871 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.

Sources & record history

Checked 27 Sep 2026
EMBL-EBI ChEBI · CHEBI:17698

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

NCBI PubChem · CID 5959 · retrieved 2026-09-27

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.