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Chemical substance record

Orphenadrine

83-98-7C18H23NO269.388 g/mol
Organic/Inorganic Small MoleculeChEBI source record

A tertiary amino compound which is the phenyl-o-tolylmethyl ether of 2-(dimethylamino)ethanol. — ChEBI

Safety references

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Identity & molecular properties

Source-linked values
CAS number83-98-7ChEBI ↗
Molecular formulaC18H23NOChEBI ↗
Molar mass269.388 g/molChEBI ↗
Monoisotopic mass269.17796 DaChEBI ↗
Formal charge0ChEBI ↗
ChEBI identifierCHEBI:7789ChEBI ↗

Cross-source molecular data

PubChem
Molar mass269.4 g/molPubChem ↗
Exact mass269.177964357 DaPubChem ↗
Computed XLogP3.8PubChem ↗
Topological polar surface area (Ų)12.5PubChem ↗
H-bond donors0PubChem ↗
H-bond acceptors2PubChem ↗
Rotatable bonds6PubChem ↗

PubChem computed values are shown separately from the ChEBI record. An exact InChIKey match was used to connect the records. Molecular descriptors do not describe a supplied product’s purity, particle size or performance.

Names & structural identifiers

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orphenadrine
N,N-dimethyl-2-[(2-methylphenyl)(phenyl)methoxy]ethanamine
QVYRGXJJSLMXQH-UHFFFAOYSA-N
Cc1ccccc1C(OCCN(C)C)c1ccccc1
InChI=1S/C18H23NO/c1-15-9-7-8-12-17(15)18(20-14-13-19(2)3)16-10-5-4-6-11-16/h4-12,18H,13-14H2,1-3H3

Names & synonyms

N,N-dimethyl-2-[(2-methylphenyl)(phenyl)methoxy]ethanamineorfenadrinaorphenadrinum

Names are supplied by ChEBI. Trade names and related synonyms may describe a broader product context.

Classification & relationships

ChEBI ontology
etherChEBI parent class · 25698 ↗tertiary amino compoundChEBI parent class · 50996 ↗
etherorganic molecular entity

Roles recorded in ChEBI

analgesicH1-receptor antagonistantiparkinson drugmuscarinic antagonistparasympatholyticmuscle relaxantNMDA receptor antagonistantidyskinesia agent

Database role annotations describe reported biological or chemical roles; they are not product approvals or recommendations for use.

Mass ↔ amount of substance

Calculated from sourced mass
Equivalent amount
0.00371212 mol

Uses 269.388 g/mol from ChEBI. Assumes the substance described by this record; no purity or concentration correction is applied.

Elemental composition

Theoretical mass fractions
C
Carbon · 18 atoms
80.26%
H
Hydrogen · 23 atoms
8.61%
O
Oxygen · 1 atom
5.94%
N
Nitrogen · 1 atom
5.20%

Calculated theoretical mass fractions from the reported formula and PubChem periodic-table atomic masses. These are not assay or purity results.

Research & patent references

Selected source associations
US2567351 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.
US2991225 · Patent reference ↗Patent cross-reference supplied by ChEBI. Association alone does not establish claim scope.
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Sources & record history

Checked 27 Sep 2026
EMBL-EBI ChEBI · CHEBI:7789

Release 255, 9 September 2026. ChEBI three-star (manually annotated) source entry. View original record ↗ · CC BY 4.0

NCBI PubChem · CID 4601 · retrieved 2026-09-27

PubCAS formats source data, connects references and computes explicitly labelled conversions. CAS cross-references are supplied by ChEBI; they do not constitute CAS verification or endorsement.

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